2. Anti-infection
  3. Penicillin-binding protein (PBP) Beta-lactamase Bacterial
  4. Zidebactam sodium salt

Zidebactam sodium salt  (Synonyms: WCK-5107 sodium salt)

Cat. No.: HY-120859A
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Zidebactam sodium salt (WCK-5107 sodium salt) is a potent β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL.

For research use only. We do not sell to patients.

CAS No. : 1706777-46-9

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Zidebactam sodium salt Related Antibodies

Top Publications Citing Use of Products

    Zidebactam sodium salt purchased from MedChemExpress. Usage Cited in: Sci Rep. 2025 Sep 29;15(1):33616.  [Abstract]

    Zidebactam (0.125-0.5 µg/mL) had a potent antibacterial effect on four E. coli strains.

    Zidebactam sodium salt purchased from MedChemExpress. Usage Cited in: Antibiotics (Basel). 2021 Nov 3;10(11):1341.

    time–kill curves of Zidebactam (ZID) (0.5 µg/mL; 24 h) on C. amalonaticus N18 and K. pneumoniae KL 12 SG.

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    Metallo-β-lactamase (MBL) Serine β-lactamase (SBL)

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    Description

    Zidebactam sodium salt (WCK-5107 sodium salt) is a potent β-lactamase inhibitor[1]. Zidebactam also is a penicillin-binding protein2 (PBP2) inhibitor with an IC50 of 0.26 μg/mL[2].

    IC50 & Target

    IC50: 0.26±0.06 μg/mL (P. aeruginosa PAO1 PBP2)[2].
    In Vitro

    Zidebactam sodium salt (WCK-5107 sodium salt) inhibits WT Enterobacteriaceae with a MIC50 of 0.25 mg/L[1].Zidebactam sodium salt (WCK-5107 sodium salt) alone exhibits variable activity when tested against E. coli (MIC50/90 0.12/0.12 mg/L) and Enterobacter spp. (MIC50/90 0.12/0.25 mg/L)[1].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Zidebactam sodium salt Related Antibodies
    Molecular Weight

    413.38

    Formula

    C13H20N5NaO7S
    CAS No.
    SMILES

    O=C([C@@H]1CCCNC1)NNC([C@@H]2CC[C@@H]3C[N@]2C(N3OS(=O)(O[Na])=O)=O)=O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
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    Zidebactam sodium salt Related Classifications

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Zidebactam1706777-46-9WCK-5107WCK5107WCK 5107Penicillin-binding protein (PBP)Beta-lactamaseBacterialβ-lactamaseInhibitorinhibitorinhibit

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