AKT-IN-17
AKT-IN-17 is a AKt inhibitor. AKT-IN-17 inhibits AKt in A549 cells, leading to Apoptosis. AKT-IN-17 can be used in non-small cell lung cancer study.
For research use only. We do not sell to patients.
- Formula: C21H21ClN4O2S
- Molecular Weight:428.94
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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AKt 105.88 μM (IC50) |
AKT-IN-17 exerts cytotoxic activity against A549 cells without influencing normal (L929) cells at their effective doses, with an IC50 176.32 μM[1].
AKT-IN-17 (44.06, 88.12, and 176.23 μM, 24 h) inhibited AKt in A549 cells with an IC50 of 105.88 μM[1].
AKT-IN-17 (176.23 μM, 24 h) induces early apoptosis of 3.26% and late apoptosis of 1.76% in A549 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:A549
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Concentration:176.23 μM
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Incubation Time:24 h
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Result:Induced early apoptosis of 3.26% and late apoptosis of 1.76% in A549 cells
Chemical Information
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Molecular Weight 428.94
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Formula C21H21ClN4O2S
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SMILES
O=C(N/N=C/C1=CC=C(N2CCCCC2)C=C1)CSC3=NC4=CC(Cl)=CC=C4O3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AKT-IN-17 Related Classifications
HY-149841 Related Classifications
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