Amino-3,5-dibromopyrazine
Based on 1 Customer Validation
Amino-3,5-dibromopyrazine (3,5-Dibromo-2-pyrazinamine) is a biochemical reagent that serves as a starting material for the synthesis of coelenterazine derivatives.
For research use only. We do not sell to patients.
- Purity: 99.98%
- CAS No.: 24241-18-7
- Formula: C4H3Br2N3
- Molecular Weight:252.90
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Biochemical agents refers to the life science research related to biological material or organic compounds.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 24241-18-7
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Appearance Solid
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Molecular Weight 252.90
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Formula C4H3Br2N3
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Color Off-white to yellow
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SMILES
BrC1=NC(Br)=C(N)N=C1
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Synonyms
3,5-Dibromo-2-pyrazinamine; 3,5-Dibromopyrazin-2-ylamine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (395.41 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5 mg/mL (19.77 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (271 KB)
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SDS (642 KB)
- English - EN (642 KB)
- Français - FR (642 KB)
- Deutsch - DE (642 KB)
- Norwegian - NO (642 KB)
- Español - ES (642 KB)
- Swedish - SV (642 KB)
- Italian - IT (642 KB)
- Korean - KR (642 KB)
- Portuguese - PT (642 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9541 mL | 19.7707 mL | 39.5413 mL | 98.8533 mL |
| 5 mM | 0.7908 mL | 3.9541 mL | 7.9083 mL | 19.7707 mL | |
| 10 mM | 0.3954 mL | 1.9771 mL | 3.9541 mL | 9.8853 mL | |
| 15 mM | 0.2636 mL | 1.3180 mL | 2.6361 mL | 6.5902 mL | |
| 20 mM | 0.1977 mL | 0.9885 mL | 1.9771 mL | 4.9427 mL | |
| 25 mM | 0.1582 mL | 0.7908 mL | 1.5817 mL | 3.9541 mL | |
| 30 mM | 0.1318 mL | 0.6590 mL | 1.3180 mL | 3.2951 mL | |
| 40 mM | 0.0989 mL | 0.4943 mL | 0.9885 mL | 2.4713 mL | |
| 50 mM | 0.0791 mL | 0.3954 mL | 0.7908 mL | 1.9771 mL | |
| 60 mM | 0.0659 mL | 0.3295 mL | 0.6590 mL | 1.6476 mL | |
| 80 mM | 0.0494 mL | 0.2471 mL | 0.4943 mL | 1.2357 mL | |
| 100 mM | 0.0395 mL | 0.1977 mL | 0.3954 mL | 0.9885 mL |
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