1. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  2. Histamine Receptor
  3. Amthamine dihydrobromide

Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity .

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Amthamine dihydrobromide

Amthamine dihydrobromide 화학구조

CAS No. : 142457-00-9

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
해외재고보유
Solution
10 mM * 1 mL in DMSO 해외재고보유
Solid
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg   견적 받기  
200 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

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Other Forms of Amthamine dihydrobromide:

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  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity [1].

분자량

319.07

화학식

C6H13Br2N3S

CAS No.
Appearance

Solid

Color

White to yellow

SMILES

NCCC1=C(C)N=C(N)S1.Br.Br

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도
In Vitro: 

H2O : 100 mg/mL (313.41 mM; Need ultrasonic)

DMSO : 83.33 mg/mL (261.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1341 mL 15.6707 mL 31.3415 mL
5 mM 0.6268 mL 3.1341 mL 6.2683 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서

Purity: 99.64%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 3.1341 mL 15.6707 mL 31.3415 mL 78.3537 mL
5 mM 0.6268 mL 3.1341 mL 6.2683 mL 15.6707 mL
10 mM 0.3134 mL 1.5671 mL 3.1341 mL 7.8354 mL
15 mM 0.2089 mL 1.0447 mL 2.0894 mL 5.2236 mL
20 mM 0.1567 mL 0.7835 mL 1.5671 mL 3.9177 mL
25 mM 0.1254 mL 0.6268 mL 1.2537 mL 3.1341 mL
30 mM 0.1045 mL 0.5224 mL 1.0447 mL 2.6118 mL
40 mM 0.0784 mL 0.3918 mL 0.7835 mL 1.9588 mL
50 mM 0.0627 mL 0.3134 mL 0.6268 mL 1.5671 mL
60 mM 0.0522 mL 0.2612 mL 0.5224 mL 1.3059 mL
80 mM 0.0392 mL 0.1959 mL 0.3918 mL 0.9794 mL
100 mM 0.0313 mL 0.1567 mL 0.3134 mL 0.7835 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
Amthamine dihydrobromide
Cat. No.:
HY-101063
수량:
MCE Japan Authorized Agent: