Anti-osteoporosis agent-2
Anti-osteoporosis agent-2 (Compound 10) is an anti-osteoporosis agent. Anti-osteoporosis agent-2 inhibits differentiation on osteoclast induced by RANKL.
For research use only. We do not sell to patients.
- CAS No.: 849693-09-0
- Formula: C20H28O6
- Molecular Weight:364.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
2.3 μM
Compound: 15
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Inhibition of LPS-induced NO production in mouse RAW264.7 cells preincubated for 2 hrs followed by LPS stimulation for 24 hrs by Griess reagent based assay
Inhibition of LPS-induced NO production in mouse RAW264.7 cells preincubated for 2 hrs followed by LPS stimulation for 24 hrs by Griess reagent based assay
|
[PMID: 34726063] |
Anti-osteoporosis agent-2 (Compound 10; 0.03-10 μM; 4-5 days) inhibits RANKL induced BMM osteoblast differentiation with an IC50 of 0.83 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 849693-09-0
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Molecular Weight 364.43
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Formula C20H28O6
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SMILES
O=C(/C(C)=C\C)O[C@H](C/C(CO)=C\CC1)[C@](C2=C)([H])[C@@](OC2=O)([H])C[C@@H]1CO
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)