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  6. Anti-osteoporosis agent-2

Anti-osteoporosis agent-2 (Compound 10) is an anti-osteoporosis agent. Anti-osteoporosis agent-2 inhibits differentiation on osteoclast induced by RANKL.

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Anti-osteoporosis agent-2

Anti-osteoporosis agent-2 Estructura química

No. CAS : 849693-09-0

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50 mg   Obtener un presupuesto  
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Anti-osteoporosis agent-2 Related Antibodies

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Descripciòn

Anti-osteoporosis agent-2 (Compound 10) is an anti-osteoporosis agent. Anti-osteoporosis agent-2 inhibits differentiation on osteoclast induced by RANKL[1].

Cellular Effect
Cell Line Type Value Description References
RAW264.7 IC50
2.3 μM
Compound: 15
Inhibition of LPS-induced NO production in mouse RAW264.7 cells preincubated for 2 hrs followed by LPS stimulation for 24 hrs by Griess reagent based assay
Inhibition of LPS-induced NO production in mouse RAW264.7 cells preincubated for 2 hrs followed by LPS stimulation for 24 hrs by Griess reagent based assay
[PMID: 34726063]
In Vitro

Anti-osteoporosis agent-2 (Compound 10; 0.03-10 μM; 4-5 days) inhibits RANKL induced BMM osteoblast differentiation with an IC50 of 0.83 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anti-osteoporosis agent-2 Related Antibodies
Peso molecular

364.43

Fòrmula

C20H28O6
No. CAS
SMILES

O=C(/C(C)=C\C)O[C@H](C/C(CO)=C\CC1)[C@](C2=C)([H])[C@@](OC2=O)([H])C[C@@H]1CO
Structure Classification
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

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Pureza y Documentación
Referencias
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Anti-osteoporosis agent-2 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anti-osteoporosis agent-2849693-09-0OthersBMMInhibitorinhibitorinhibit

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Nombre del producto:
Anti-osteoporosis agent-2
Cat. No.:
HY-N11514
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