AACT Antibody (YA1103)
(Synonyms: SERPINA3; AACT; GIG24; GIG25; Alpha-1-antichymotrypsin; ACT; Cell growth-inhibiting gene 24/25 protein; Serpin A3)AACT Antibody (YA1103) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to AACT.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.37.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:100-1:200 |
Product Details
AACT Antibody (YA1103) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to AACT.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 47 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 48 kDa
Recombinant protein of human AACT
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.37.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
AACT is an Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2
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Subcellular Localization
Secreted
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Expression
Tissue_specificity:Plasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains -
Isoforms & Post-Translational Modification
P01011 has 3 isomers: P01011-1: 47651 Da (predicted); P01011-2: 24034 Da (predicted); P01011-3: 10717 Da (predicted).
N- and O-glycosylated -
Subunit
Interacts with DNAJC1
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SwissProt ID
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Synonyms
SERPINA3; AACT; GIG24; GIG25; Alpha-1-antichymotrypsin; ACT; Cell growth-inhibiting gene 24/25 protein; Serpin A3
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Research Field
Neuroscience
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