SERPINA3 - serpin family A member 3 Gene
Also Known as ACT; AACT; GIG24; GIG25
Species: Homo sapiens
About SERPINA3
This gene has 9 transcripts (splice variants), 214 orthologues and 36 paralogues. Biased expression in liver (RPKM 989.5), gall bladder (RPKM 89.2) and 4 other tissues.
Summary
The protein encoded by this gene is a member of the Serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of Serpin genes located on the q arm of chromosome 14. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jun 2020]
SERPINA3 Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_001085.5 | NP_001076.2 | alpha-1-antichymotrypsin precursor |
| NM_001384672.1 | NP_001371601.1 | alpha-1-antichymotrypsin precursor |
| NM_001384673.1 | NP_001371602.1 | alpha-1-antichymotrypsin precursor |
| NM_001384674.1 | NP_001371603.1 | alpha-1-antichymotrypsin precursor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
12709365 | GOA |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in extracellular space |
IDA
IDA: Inferred from direct assay
|
25645918 | GOA |
SERPINA3 Protein Structure
Serpin: Serpin (serine protease inhibitor) (52 - 420)
- 0
- 100
- 200
- 300
- 400
- 423 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
alpha-1-antichymotrypsin |
|
SERPINA3 Protein-protein interaction Information
|
Type
|
Protein Name | Protein ID | Interactor | Interactor Species | Interactor ID | Detection Method | References |
|---|---|---|---|---|---|---|---|
|
Intra
|
SERPINA3 | P01011 | LAMP2 | Homo sapiens | P13473-2 | 32814053 | |
|
Intra
|
SERPINA3 | P01011 | LAMP2 | Homo sapiens | P13473-2 | 32814053 | |
|
Intra
|
SERPINA3 | P01011 | LAMP2 | Homo sapiens | P13473-2 | 32814053 | |
|
Intra
|
SERPINA3 | P01011 | VPS33A | Homo sapiens | Q96AX1 | 32814053 | |
|
Intra
|
SERPINA3 | P01011 | VPS33A | Homo sapiens | Q96AX1 | 32814053 | |
|
Intra
|
SERPINA3 | P01011 | VPS33A | Homo sapiens | Q96AX1 | 32814053 | |
|
Intra
|
SERPINA3 | P01011 | SH3GLB1 | Homo sapiens | Q9Y371 | 32814053 | |
|
Intra
|
SERPINA3 | P01011 | SH3GLB1 | Homo sapiens | Q9Y371 | 32814053 | |
|
Intra
|
SERPINA3 | P01011 | SH3GLB1 | Homo sapiens | Q9Y371 | 32814053 | |
|
Intra
|
SERPINA3 | P01011 | DNAJC1 | Homo sapiens | Q96KC8 | 14668352 | |
|
Intra
|
SERPINA3 | P01011 | DNAJC1 | Homo sapiens | Q96KC8 | 14668352 | |
|
Intra
|
SERPINA3 | P01011 | DNAJC1 | Homo sapiens | Q96KC8 | 14668352 | |
|
Intra
|
SERPINA3 | P01011 | STUB1 | Homo sapiens | Q9UNE7 | 32814053 | |
|
Intra
|
SERPINA3 | P01011 | STUB1 | Homo sapiens | Q9UNE7 | 32814053 | |
|
Intra
|
SERPINA3 | P01011 | STUB1 | Homo sapiens | Q9UNE7 | 32814053 | |
|
Intra
|
SERPINA3 | P01011 | CASP6 | Homo sapiens | P55212 | 32814053 | |
|
Intra
|
SERPINA3 | P01011 | CASP6 | Homo sapiens | P55212 | 32814053 | |
|
Intra
|
SERPINA3 | P01011 | CASP6 | Homo sapiens | P55212 | 32814053 | |
|
Intra
|
SERPINA3 | P01011 | APP | Homo sapiens | P05067 | 32814053 | |
|
Intra
|
SERPINA3 | P01011 | APP | Homo sapiens | P05067 | 32814053 | |
|
Intra
|
SERPINA3 | P01011 | APP | Homo sapiens | P05067 | 32814053 |
Recombinant SERPINA3 Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P71054 | Serpin A3 Protein, Human (K267R, HEK293, His) | P01011 (H24-A423, K267R) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P73412 | Serpin A3 Protein, Human (HEK293, His) | NP_001076.2 (N26-A423) | ≥ 95%, as determined by reducing SDS-PAGE. |
SERPINA3 Antibodies
| Cat. No. | Product Name | Application | Reactivity |
|---|---|---|---|
| HY-P81358 | AACT Antibody (YA1103) | IHC-P | Human |
| HY-P81358A | AACT Antibody (YA1103)(PBS only) | IHC-P | Human |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Malignant Fibrous Histiocytoma |
|
|
| Alpha-1-Antitrypsin Deficiency |
|
|
| Fibrosarcoma Of Bone |
|
|
| Benign Giant Cell Tumor |
|
|
| Vascular Dementia |
|
|
| Connective Tissue Benign Neoplasm |
|
|
| Plasma Protein Metabolism Disease |
|
|
| Hepatoid Adenocarcinoma |
|
|
| Reticulohistiocytic Granuloma |
|
|
| Ameloblastoma |
|
|
| Chromosomal Duplication Syndrome |
|
|
| Non-Langerhans-Cell Histiocytosis |
|
|
| Bone Benign Neoplasm |
|
|
| Malignant Inflammatory Fibrous Histiocytoma |
|
|
| Congenital Epulis |
|
|
| Communicating Hydrocephalus |
|
|
| Histiocytosis |
|
|
| Acinar Cell Cystadenocarcinoma |
|
|
| Temporal Arteritis |
|
|
| Nodular Tenosynovitis |
|
|
| Xanthogranulomatous Pyelonephritis |
|
|
| Male Reproductive Organ Cancer |
|
|
| Solitary Mastocytoma Of The Skin |
|
|
| Histiocytic And Dendritic Cell Cancer |
|
|
| Epulis |
|
|
| Adenosquamous Gallbladder Carcinoma |
|
|
| Impetigo Herpetiformis |
|
|
| Pancreatic Acinar Cell Adenocarcinoma |
|
|
| Tenosynovial Giant Cell Tumor |
|
|
| Mixed Hepatoblastoma |
|
|
| Heart Cancer |
|
|
| Creutzfeldt-Jakob Disease |
|
|
| Amyloidosis |
|
|
| Liver Sarcoma |
|
|
| Breast Cyst |
|
|
| Pancreas Sarcoma |
|
|
| Salivary Gland Carcinoma |
|
|
| Ovarian Mucinous Adenocarcinoma |
|
|
| Malignant Mesenchymoma |
|
|
| Ovarian Cystadenocarcinoma |
|
|
| Myasthenic Syndrome, Congenital, 2c, Associated With Acetylcholine Receptor Deficiency |
|
|
| Proliferative Fasciitis |
|
|
| Chondroid Chordoma |
|
|
| Adamantinous Craniopharyngioma |
|
|
| Pancreatoblastoma |
|
|
| Encephalopathy, Familial, With Neuroserpin Inclusion Bodies |
|
|
| Bone Sarcoma |
|
|
| Peripheral Nerve Schwannoma |
|
|
| Male Reproductive System Disease |
|
|
| Gastric Squamous Cell Carcinoma |
|
|
| Cholinergic Urticaria |
|
|
| Multicentric Reticulohistiocytosis |
|
|
| Xanthogranulomatous Cholecystitis |
|
|
| Scrotum Neoplasm |
|
|
| Soft Tissue Chondroma |
|
|
| Lipoadenoma |
|
|
| Thyroid Gland Hurthle Cell Carcinoma |
|
|
| Cerebral Amyloid Angiopathy, Cst3-Related |
|
|
| Cerebral Amyloid Angiopathy, App-Related |
|
|
| Type C Thymoma |
|
|
| Testicular Malignant Germ Cell Cancer |
|
|
| Cerebrovascular Disease |
|
|
| Lethal Midline Granuloma |
|
|
| Granular Cell Tumor |
|
|
| Papillary Cystadenocarcinoma |
|
|
| Fibrous Histiocytoma |
|
|
| Combat Disorder |
|
|
| Chronic Inducible Urticaria |
|
|
| Cystadenoma |
|
|
| Lymph Node Disease |
|
|
| Miliaria Crystallina |
|
|
| Exfoliation Syndrome |
|
|
| Cerebral Arterial Disease |
|
|
| Tricuspid Valve Stenosis |
|
|
| Cone-Rod Dystrophy, X-Linked, 2 |
|
|
| Bladder Sarcoma |
|
|
| Proliferative Type Fibrocystic Change Of Breast |
|
|
| Immunoglobulin Heavy-And-Light Chain |
|
|
| Cardiovascular Organ Benign Neoplasm |
|
|
| Central Nervous System Vasculitis |
|
|
| Partial Optic Atrophy |
|
|
| Gingival Disease |
|
|
| Integumentary System Disease |
|
|
| Psoriasis 14, Pustular |
|
|
| Bronchiectasis |
|
|
| Fibroma |
|
|
| Nonaka Myopathy |
|
|
| Cerebral Amyloid Angiopathy, Itm2b-Related, 2 |
|
|
| Mild Cognitive Impairment |
|
|
| Malignant Spindle Cell Melanoma |
|
|
| Testicular Yolk Sac Tumor |
|
|
| Arteries, Anomalies Of |
|
|
| Liver Disease |
|
|
| Toxic Encephalopathy |
|
|
| Subjective Cognitive Decline |
|
|
| Cecal Disease |
|
|
| Bronchial Disease |
|
|
| Disease Of Mental Health |
|
|
| Verruciform Xanthoma Of Skin |
|
|
| Muscular Disease |
|
|
| Fibrosarcomatous Osteosarcoma |
|
|
| Pulmonary Emphysema |
|
|
| Ossifying Fibroma |
|
|
| Skeletal Muscle Cancer |
|
|
| Polyclonal Hypergammaglobulinemia |
|
|
| Bone Inflammation Disease |
|
|
| Parasitic Protozoa Infectious Disease |
|
|
| Dementia |
|
|
| Muscle Cancer |
|
|
| Microglandular Adenosis |
|
|
| Sarcomatoid Squamous Cell Skin Carcinoma |
|
|
| Malignant Granular Cell Myoblastoma |
|
|
| Pleomorphic Xanthoastrocytoma |
|
|
| Histiocytosis-Lymphadenopathy Plus Syndrome |
|
|
| Autoimmune Disease Of Musculoskeletal System |
|
|
| Kuru |
|
|
| Giant Cell Reparative Granuloma |
|
|
| Pleomorphic Liposarcoma |
|
|
| Cutaneous Fibrous Histiocytoma |
|
|
| Autoimmune Disease Of Central Nervous System |
|
|
| Partial Motor Epilepsy |
|
|
| Juvenile Xanthogranuloma |
|
|
| Reproductive System Disease |
|
|
| Gm1-Gangliosidosis, Type Ii |
|
|
| Mixed Cell Type Cancer |
|
|
| Coffin-Siris Syndrome 2 |
|
|
| Kidney Rhabdoid Cancer |
|
|
| Prostate Disease |
|
|
| Geographic Tongue |
|
|
| Cerebral Degeneration |
|
|
| Non-Severe Covid-19 |
|
|
| Phacogenic Glaucoma |
|
|
| Glutamate Formiminotransferase Deficiency |
|
|
| Inherited Metabolic Disorder |
|
|
| Carbohydrate Metabolic Disorder |
|
|
| Spinocerebellar Ataxia 34 |
|
|
| Autoimmune Disease Of Skin And Connective Tissue |
|
|
| Chondrosarcoma |
|
|
| Ovarian Mucinous Cystadenocarcinoma |
|
|
| Coronavirus Infectious Disease |
|
|
| Steroid-Induced Glaucoma |
|
|
| Chondroblastic Osteosarcoma |
|
|
| Syndromic X-Linked Intellectual Disability Cabezas Type |
|
|
| Cell Type Benign Neoplasm |
|
|
| Cerebellar Astrocytoma |
|
|
| Male Reproductive Organ Benign Neoplasm |
|
|
| Atrophic Glossitis |
|
|
| Gerstmann-Straussler Disease |
|
|
| Chronic Pyelonephritis |
|
|
| Fatal Familial Insomnia |
|
|
| Breast Secretory Carcinoma |
|
|
| Leiomyosarcoma |
|
|
| Heart Sarcoma |
|
|
| Pustulosis Of Palm And Sole |
|
|
| Pulmonary Disease, Chronic Obstructive |
|
|
| Arteriolosclerosis |
|
|
| Alzheimer Disease, Familial, 1 |
|
|
| Glucose Metabolism Disease |
|
|
| Hypotrichosis 8 |
|
|
| Primary Bacterial Infectious Disease |
|
|
| Acinar Cell Carcinoma |
|
|
| Chromosomal Disease |
|
|
| Mucoepidermoid Carcinoma |
|
|
| Alzheimer Disease 2 |
|
|
| Plasmodium Vivax Malaria |
|
|
| Connective Tissue Cancer |
|
|
| Heparin Cofactor Ii Deficiency |
|
|
| Epithelioid Leiomyosarcoma |
|
|
| Syringocystadenoma Papilliferum |
|
|
| Prostatic Hypertrophy |
|
|
| Immune System Disease |
|
|
| Phobic Disorder |
|
|
| Acquired Metabolic Disease |
|
|
| Hypersensitivity Reaction Type Iv Disease |
|
|
| Down Syndrome |
|
|
| Myositis |
|
|
| Inclusion Body Myositis |
|
|
| Clear Cell Chondrosarcoma |
|
|
| Salivary Gland Disease |
|
|
| Chordoma |
|
|
| Normal Pressure Hydrocephalus |
|
|
| Bone Giant Cell Tumor |
|
|
| Aspiration Pneumonitis |
|
|
| Central Nervous System Disease |
|
|
| Mesenchymal Cell Neoplasm |
|
|
| Paranoid Schizophrenia |
|
|
| Arthrogryposis, Distal, Type 4 |
|
|
| Cerebral Amyloid Angiopathy, Itm2b-Related, 1 |
|
|
| Adenoid Cystic Carcinoma |
|
|
| Disease By Infectious Agent |
|
|
| Lung Disease |
|
|
| Sebaceous Gland Disease |
|
|
| Sensory System Disease |
|
|
| Amyloidosis, Finnish Type |
|
|
| Paralytic Poliomyelitis |
|
|
| Skin Benign Neoplasm |
|
|
| Breast Benign Neoplasm |
|
|
| Thoracic Benign Neoplasm |
|
|
| Prostatic Hyperplasia, Benign |
|
|
| Ovary Adenocarcinoma |
|
|
| Gastrointestinal System Disease |
|
|
| Respiratory System Disease |
|
|
| Mammary Analogue Secretory Carcinoma |
|
|
| Middle Ear Disease |
|
|
| Heavy Chain Disease |
|
|
| Obstructive Jaundice |
|
|
| Primary Cutaneous Amyloidosis |
|
|
| Liver Cirrhosis |
|
|
| Prostate Cancer |
|
|
| Cerebral Atherosclerosis |
|
|
| Lung Giant Cell Carcinoma |
|
|
| Salivary Gland Adenoid Cystic Carcinoma |
|
|
| Pancreatic Endocrine Carcinoma |
|
|
| Chronic Meningitis |
|
|
| Gastrointestinal System Benign Neoplasm |
|
|
| Severe Covid-19 |
|
|
| Meningothelial Meningioma |
|
|
| Malignant Fibrous Histiocytoma Of Bone |
|
|
| Periodontitis |
|
|
| Malignant Epithelioid Hemangioendothelioma |
|
|
| Vegetable Allergy |
|
|
| Amino Acid Metabolic Disorder |
|
|
| Muscle Tissue Disease |
|
|
| Olivopontocerebellar Atrophy |
|
|
| Pancreatitis |
|
|
| Amelanotic Melanoma |
|
|
| Platelet Aggregation, Spontaneous |
|
|
| Dialysis-Related Amyloidosis |
|
|
| C1 Inhibitor Deficiency |
|
|
| Physical Urticaria |
|
|
| Childhood-Onset Asthma |
|
|
| Pyelitis |
|
|
| Multiple System Atrophy 1 |
|
|
| Overnutrition |
|
|
| Lymphatic System Disease |
|
|
| Sympathetic Ophthalmia |
|
|
| Retinal Hemangioblastoma |
|
|
| Reticulosarcoma |
|
|
| Central Nervous System Benign Neoplasm |
|
|
| Histiocytic Sarcoma |
|
|
| Macular Degeneration, Age-Related, 1 |
|
|
| Hematuria, Benign Familial |
|
|
| Bronchopneumonia |
|
|
| Aortic Disease |
|
|
| Hydrocephalus |
|
|
| Iris Disease |
|
|
| Serum Amyloid A Amyloidosis |
|
|
| Tonsil Cancer |
|
|
| Opisthorchiasis |
|
|
| Sebaceous Adenoma |
|
|
| Vasculitis |
|
|
| Vein Disease |
|
|
| Pasteurellosis |
|
|
| Skin Tag |
|
|
| Endocrine System Disease |
|
|
| Pulmonary Artery Disease |
|
|
| Biliary Tract Disease |
|
|
| Collagen Disease |
|
|
| Bile Duct Disease |
|
|
| Thrombosis |
|
|
| Wrinkly Skin Syndrome |
|
|
| Gingival Hypertrophy |
|
|
| Hemoglobin E Disease |
|
|
| Secondary Progressive Multiple Sclerosis |
|
|
| Nonobstructive Coronary Artery Disease |
|
|
| Breast Malignant Phyllodes Tumor |
|
|
| Sarcoidosis 1 |
|
|
| Langerhans Cell Histiocytosis |
|
|
| Wild-Type Amyloidosis |
|
|
| Glycoproteinosis |
|
|
| Pancreas Disease |
|
|
| Skull Base Meningioma |
|
|
| Speech And Communication Disorders |
|
|
| Skull Base Cancer |
|
|
| Social Phobia |
|
|
| Myocardial Infarction |
|
|
| Pleomorphic Lipoma |
|
|
| Cholera |
|
|
| Erdheim-Chester Disease |
|
|
| Siderosis |
|
|
| Cranial Nerve Disease |
|
|
| Prion Disease |
|
|
| Cavernous Hemangioma |
|
|
| Dermatofibrosarcoma Protuberans |
|
|
| Bacterial Pneumonia |
|
|
| Physical Disorder |
|
|
| Myxofibrosarcoma |
|
|
| Mitral Valve Stenosis |
|
|
| Islet Cell Tumor |
|
|
| Trichuriasis |
|
|
| Apocrine Adenocarcinoma |
|
|
| Oropharynx Cancer |
|
|
| Parasitic Helminthiasis Infectious Disease |
|
|
| Low Grade Glioma |
|
|
| Prostatic Adenoma |
|
|
| Farmer'S Lung |
|
|
| Vascular Cancer |
|
|
| Uveal Disease |
|
|
| Impetigo |
|
|
| Degeneration Of Macula And Posterior Pole |
|
|
| Autoimmune Disease Of Cardiovascular System |
|
|
| Chronic Wasting Disease |
|
|
| Heart Valve Disease |
|
|
| Adult-Onset Still'S Disease |
|
|
| Interdigitating Dendritic Cell Sarcoma |
|
|
| Dementia, Lewy Body |
|
|
| Epithelioid Sarcoma |
|
|
| Mental Depression |
|
|
| Endocrine Gland Cancer |
|
|
| Ovarian Serous Cystadenocarcinoma |
|
|
| Sebaceous Gland Neoplasm |
|
|
| Angiosarcoma |
|
|
| Perivascular Tumor |
|
|
| Eye Degenerative Disease |
|
|
| Secretory Meningioma |
|
|
| Mucinous Cystadenocarcinoma |
|
|
| Dedifferentiated Liposarcoma |
|
|
| Autoimmune Disease Of Gastrointestinal Tract |
|
|
| Immune Deficiency Disease |
|
|
| Human Immunodeficiency Virus Infectious Disease |
|
|
| Blood Coagulation Disease |
|
|
| Specific Developmental Disorder |
|
|
| Substance Abuse |
|
|
| Urinary System Disease |
|
|
| Extrinsic Cardiomyopathy |
|
|
| Aspiration Pneumonia |
|
|
| Atypical Depressive Disorder |
|
|
| Spinal Cord Disease |
|
|
| Cellular Myxoid Liposarcoma |
|
|
| Pancreatic Cancer |
|
|
| Gastric Cancer |
|
|
| Supranuclear Palsy, Progressive, 1 |
|
|
| Hypersensitivity Reaction Type Iii Disease |
|
|
| Lung Cancer |
|
|
| Sarcoma |
|
|
| Scrapie |
|
|
| Pleomorphic Rhabdomyosarcoma |
|
|
| Breast Carcinoma In Situ |
|
|
| Wernicke-Korsakoff Syndrome |
|
|
| Malignant Ovarian Surface Epithelial-Stromal Neoplasm |
|
|
| Intracranial Berry Aneurysm |
|
|
| Onchocerciasis |
|
|
| Malaria |
|
|
| Retinal Vascular Occlusion |
|
|
| Lymphadenitis |
|
|
| Spindle Cell Sarcoma |
|
|
| Commensal Bacterial Infectious Disease |
|
|
| Substance Dependence |
|
|
| Smooth Muscle Tumor |
|
|
| In Situ Carcinoma |
|
|
| Juvenile Rheumatoid Arthritis |
|
|
| Demyelinating Disease |
|
|
| Psychotic Disorder |
|
|
| Ductal Carcinoma In Situ |
|
|
| Meningoencephalitis |
|
|
| Thoracic Cancer |
|
|
| Hemangiopericytoma, Malignant |
|
|
| Breast Fibroadenoma |
|
|
| Retinal Vascular Disease |
|
|
| Psoriasis |
|
|
| Pre-Malignant Neoplasm |
|
|
| Retinal Disease |
|
|
| Primary Progressive Multiple Sclerosis |
|
|
| Diffuse Astrocytoma |
|
|
| Well-Differentiated Liposarcoma |
|
|
| Leukocyte Disease |
|
|
| Peripheral Nervous System Disease |
|
|
| Chronic Asthma |
|
|
| Corneal Disease |
|
|
| Intestinal Disease |
|
|
| Phenylketonuria |
|
|
| Panuveitis |
|
|
| Bone Cancer |
|
|
| Lymphatic System Cancer |
|
|
| Gallbladder Disease |
|
|
| Neurilemmoma |
|
|
| Thrombophlebitis |
|
|
| Adenosquamous Carcinoma |
|
|
| Malignant Exocrine Pancreas Neoplasm |
|
|
| Gastrointestinal System Cancer |
|
|
| Rheumatoid Arthritis |
|
|
| Asthma |
|
|
| Papilledema |
|
|
| Vasculopathy, Retinal, With Cerebral Leukoencephalopathy And Systemic Manifestations |
|
|
| Lipoid Nephrosis |
|
|
| Hereditary Angioedema |
|
|
| Breast Adenocarcinoma |
|
|
| Lipid Storage Disease |
|
|
| Critical Covid-19 |
|
|
| Nose Disease |
|
|
| Intraocular Pressure Quantitative Trait Locus |
|
|
| Connective Tissue Disease |
|
|
| Systolic Heart Failure |
|
|
| Macular Holes |
|
|
| Congenital Fibrosarcoma |
|
|
| Childhood Fibrosarcoma |
|
|
| Filariasis |
|
|
| Lipomatosis, Multiple |
|
|
| Sphingolipidosis |
|
|
| Bacterial Infectious Disease |
|
|
| Anterior Uveitis |
|
|
| Pseudosarcomatous Fibromatosis |
|
|
| Schizophrenia |
|
|
| Aortic Valve Disease 2 |
|
|
| Mast Cell Neoplasm |
|
|
| Sweat Gland Disease |
|
|
| Splenic Disease |
|
|
| Leprosy 3 |
|
|
| Female Reproductive System Disease |
|
|
| Cerebral Arteriopathy, Autosomal Dominant, With Subcortical Infarcts And Leukoencephalopathy, Type 1 |
|
|
| Cardiovascular System Disease |
|
|
| Chronic Fatigue Syndrome |
|
|
| Adult Respiratory Distress Syndrome |
|
|
| Ovary Epithelial Cancer |
|
|
| Nutritional Deficiency Disease |
|
|
| Aortic Aneurysm, Familial Abdominal, 1 |
|
|
| Neuroma |
|
|
| Moyamoya Disease 1 |
|
|
| Lymphangioma |
|
|
| Respiratory Failure |
|
|
| Mycobacterium Tuberculosis 1 |
|
|
| Schizoaffective Disorder |
|
|
| Nervous System Disease |
|
|
| Hypersensitivity Vasculitis |
|
|
| Stroke, Ischemic |
|
|
| Bone Disease |
|
|
| Diabetes Mellitus |
|
|
| Tooth Resorption |
|
|
| Alcohol Use Disorder |
|
|
| Neutrophilic Dermatosis, Acute Febrile |
|
|
| Retinal Artery Occlusion |
|
|
| Dengue Disease |
|
|
| Giant Cell Glioblastoma |
|
|
| Mood Disorder |
|
|
| Urinary Tract Infection |
|
|
| Henoch-Schoenlein Purpura |
|
|
| Movement Disease |
|
|
| Endometrial Adenocarcinoma |
|
|
| Cystadenocarcinoma |
|
|
| Intrinsic Cardiomyopathy |
|
|
| Parkinson Disease, Late-Onset |
|
|
| Peripheral Nervous System Neoplasm |
|
|
| Skin Disease |
|
|
| Breast Disease |
|
|
| Glaucoma, Primary Open Angle |
|
|
| Dysentery |
|
|
| Crohn'S Disease |
|
|
| Peripheral Vascular Disease |
|
|
| Placenta Disease |
|
|
| Dry Eye Syndrome |
|
|
| Transient Cerebral Ischemia |
|
|
| Mitral Valve Disease |
|
|
| Allergic Disease |
|
|
| Viral Infectious Disease |
|
|
| Colorectal Cancer |
|
|
| Interstitial Lung Disease |
|
|
| Coccidiosis |
|
|
| Myopathy |
|
|
| Carney Complex Variant |
|
|
| Viral Encephalitis |
|
|
| Upper Respiratory Tract Disease |
|
|
| Intestinal Benign Neoplasm |
|
|
| Eyelid Disease |
|
|
| Suppression Of Tumorigenicity 12 |
|
|
| Heart Conduction Disease |
|
|
| Mouth Disease |
|
|
| Blood Platelet Disease |
|
|
| Teeth Hard Tissue Disease |
|
|
| Optic Nerve Disease |
|
|
| Pilocytic Astrocytoma |
|
|
| Lacrimal Apparatus Disease |
|
|
| Microvascular Complications Of Diabetes 5 |
|
|
| Vascular Disease |
|
|
| Eye Disease |
|
|
| Contact Dermatitis |
|
|
| Myofibrillar Myopathy |
|
|
| Central Nervous System Cancer |
|
|
| Embryonal Rhabdomyosarcoma |
|
|
| Colonic Benign Neoplasm |
|
|
| Lysosomal Storage Disease |
|
|
| Anaplastic Astrocytoma |
|
|
| Colonic Disease |
|
|
| Bone Remodeling Disease |
|
|
| Pelvic Varices |
|
|
| Bile Duct Adenocarcinoma |
|
|
| Spinal Disease |
|
|
| Lipid Metabolism Disorder |
|
|
| Mucolipidosis |
|
|
| Agnosia |
|
|
| Hematologic Cancer |
|
|
| Germ Cell Cancer |
|
|
| Heart Disease |
|
|
| Arteriovenous Malformation |
|
|
| Gliosarcoma |
|
|
| Gastrointestinal Stromal Tumor |
|
|
| Endocrine Organ Benign Neoplasm |
|
|
| Pick Disease Of Brain |
|
|
| Lens Disease |
|
|
| Keratitis, Hereditary |
|
|
| Motor Neuron Disease |
|
|
| Amyotrophic Lateral Sclerosis 1 |
|
|
| Lipoprotein Quantitative Trait Locus |
|
|
| Malignant Astrocytoma |
|
|
| Autosomal Dominant Cerebellar Ataxia |
|
|
| Deficiency Anemia |
|
|
| Frontotemporal Dementia |
|
|
| Huntington Disease |
|
|
| Pancreatic Ductal Adenocarcinoma |
|
|
| Cerebellar Disease |
|
|
| Ehlers-Danlos Syndrome |
|
|
| Hemoglobinopathy |
|
|
| Body Mass Index Quantitative Trait Locus 11 |
|
|
| Interstitial Lung Disease 2 |
|
|
| Breast Cancer |
|
|
| Alcohol Dependence |
|
|
| Meningioma, Familial |
|
|
| Migraine With Or Without Aura 1 |
|
|
| Inflammatory Bowel Disease |
|
|
| Dermatitis, Atopic |
|
|
| Dilated Cardiomyopathy |
|
|
| Hypertension, Essential |
|
|
| Lymphoma, Non-Hodgkin, Familial |
|
|
| Type 2 Diabetes Mellitus |
|
|
| Wilms Tumor 1 |
|
|
| Hypertrophic Cardiomyopathy |
|
|
| Celiac Disease 1 |
|
|
| Attention Deficit-Hyperactivity Disorder |
|
|
| Leukemia, Acute Myeloid |
|
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | SERPINA3 | RGD | RGD:3747 |
| Macaca mulatta | SERPINA3 | VGNC | VGNC:99238 |
| Felis catus | SERPINA3 | VGNC | VGNC:80848 |
| Others | SERPINA3 | NCBI |