Artemin Antibody (YA2155)(PBS only)
(Synonyms: Enovin; Neublastin)Artemin Antibody (YA2155) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Artemin.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IP
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IP
IP: Immunoprecipitation
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|---|
| Dilution Ratio | 1:1000-1:5000 | 1:10-1:100 | 50-1:100 |
Product Details
Artemin Antibody (YA2155) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Artemin.
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Host Rabbit
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 23 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 23 kDa
A synthetic peptide of human Artemin aa189-202.
Affinity Purified
Non-conjugated
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Artemin is a Growth factor that supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Acts by binding to its coreceptor, GFRA3, leading to autophosphorylation and activation of the RET receptor. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue[1][2][3].
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Subcellular Localization
Secreted
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Expression
Tissue_specificity:Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain -
Isoforms & Post-Translational Modification
Q5T4W7 has 3 isomers: Q5T4W7-1: 22878 Da (predicted); Q5T4W7-2: 24471 Da (predicted); Q5T4W7-3: 23616 Da (predicted).
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Subunit
Homodimer; disulfide-linked (PubMed:16765900, PubMed:31535977). Interacts with GFRA3 coreceptor and RET: forms a 2:2:2 ternary complex composed of ARTN ligand, GFRA3 and RET receptor (PubMed:31535977)
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SwissProt ID
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Synonyms
Enovin; Neublastin
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Research Field
Neuroscience
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