Artemin Antibody (YA2155)(PBS only)

Cat. No.: HY-P82410A: Data Sheet User Guide for Antibodies
FAQs
Technical Support

Artemin Antibody (YA2155) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Artemin.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

Artemin Antibody (YA2155) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Artemin.

Host

Rabbit

Molecular Weight

Predicted band size: 23 kDa;

Observed band size: 23 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q5T4W7

Gene ID

9048 [NCBI]

Immunogen

A synthetic peptide of human Artemin aa189-202.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:5000
IP IP: Immunoprecipitation	1:10-1:100
IHC-P IHC-P: Immunohistochemistry-Paraffin	50-1:100

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Growth factor that supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain (PubMed:10583383, PubMed:9883723). Acts by binding to its coreceptor, GFRA3, leading to autophosphorylation and activation of the RET receptor (PubMed:31535977). Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue (By similarity)

Subcellular Localization：Secreted

Expression：
Tissue_specificity:Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas, heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain

Isoforms & Post-Translational Modification：Q5T4W7 has 3 isomers: Q5T4W7-1: 22878 Da (predicted); Q5T4W7-2: 24471 Da (predicted); Q5T4W7-3: 23616 Da (predicted).

Subunit：Homodimer; disulfide-linked (PubMed:16765900, PubMed:31535977). Interacts with GFRA3 coreceptor and RET: forms a 2:2:2 ternary complex composed of ARTN ligand, GFRA3 and RET receptor (PubMed:31535977)

Research Field

Neuroscience

Synonyms

Enovin; Neublastin

Documentation

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/mda-mb-231-cell.html [Content Brief]