BLCAP Antibody (YA7049)

Cat. No.: HY-P87366: Data Sheet User Guide for Antibodies
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BLCAP Antibody (YA7049) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to BLCAP.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

BLCAP Antibody (YA7049) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to BLCAP.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 10kDa;

Observed band size: 10kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Rat

SwissProt ID

P62952

Immunogen

Synthetic peptide within Human BLCAP aa 38-87 / 87.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:2000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:200

Sensitivity	Endogenous	Purity	Protein G affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Supplied in 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Acts as a tumor suppressor; induces growth arrest at G(1)/S checkpoint and apoptosis via RB1-dependent and p53/TP53- and NF-kappa-B-independent mechanisms (PubMed:16675915, PubMed:17031575, PubMed:21844121, PubMed:26986503). Modulates expression of genes involved in the regulation of proliferation, cell cycle and apoptosis (PubMed:17031575, PubMed:21844121, PubMed:26986503)

Subcellular Localization：Cytoplasm,Nucleus,Membrane

Expression：
Tissue_Specificity: Cervical tissues (at protein level) (PubMed:22969892). Urothelium (at protein level) (PubMed:19783793, PubMed:29190807). Endothelial cells of urinary bladder vessels (at protein level) (PubMed:19783793). Urinary bladder stromal cells (at protein level) (PubMed:19783793). Cervical tissues (PubMed:16675915). Kidney (PubMed:11072240). Ubiquitous (PubMed:19908260)

Subunit：Interacts with RB1 (phosphorylated and unphosphorylated) (PubMed:26986503)

Synonyms

Bc10 antibody; Bladder cancer 10 kDa protein antibody; Bladder cancer related protein (10kD) antibody; Bladder cancer-associated protein antibody; BLCAP antibody; BLCAP_HUMAN antibody

Documentation

User Guide for Antibodies (1077 KB)