BLCAP Antibody (YA7049)
(Synonyms: Bc10 antibody; Bladder cancer 10 kDa protein antibody; Bladder cancer related protein (10kD) antibody; Bladder cancer-associated protein antibody; BLCAP antibody; BLCAP_HUMAN antibody)BLCAP Antibody (YA7049) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to BLCAP.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Rat
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Formulation:
Supplied in 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|---|
| Dilution Ratio | 1:1000-1:2000 | 1:50-1:200 | 1:50-1:200 |
Product Details
BLCAP Antibody (YA7049) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to BLCAP.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Rat
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Observed Molecular WeightObserved band size: 10kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 10kDa
Synthetic peptide within Human BLCAP aa 38-87 / 87.
Endogenous
Protein G affinity purified.
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
BLCAP acts as a tumor suppressor; induces growth arrest at G(1)/S checkpoint and apoptosis via RB1-dependent and p53/TP53- and NF-kappa-B-independent mechanisms. Modulates expression of genes involved in the regulation of proliferation, cell cycle and apoptosis[1][2][3][4].
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Subcellular Localization
Cytoplasm,Nucleus,Membrane
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Expression
Tissue_Specificity: Cervical tissues (at protein level) (PubMed:22969892). Urothelium (at protein level) (PubMed:19783793, PubMed:29190807). Endothelial cells of urinary bladder vessels (at protein level) (PubMed:19783793). Urinary bladder stromal cells (at protein level) (PubMed:19783793). Cervical tissues (PubMed:16675915). Kidney (PubMed:11072240). Ubiquitous (PubMed:19908260) -
Subunit
Interacts with RB1 (phosphorylated and unphosphorylated) (PubMed:26986503)
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SwissProt ID
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Synonyms
Bc10 antibody; Bladder cancer 10 kDa protein antibody; Bladder cancer related protein (10kD) antibody; Bladder cancer-associated protein antibody; BLCAP antibody; BLCAP_HUMAN antibody
Documentation
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