C Reactive Protein Antibody (YA940)
(Synonyms: CRP; PTX1; C-reactive protein)C Reactive Protein Antibody (YA940) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to C Reactive Protein.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Conjugation:
Non-conjugated
Applications
| Application |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|
| Dilution Ratio | 1:10000 |
Product Details
C Reactive Protein Antibody (YA940) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to C Reactive Protein.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 25 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 25 kDa
Synthetic peptide.
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
C Reactive Protein is a Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells
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Subcellular Localization
Secreted
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Expression
Tissue_specificity:present in blood plasma
Induction:The concentration of CRP in plasma increases greatly during acute phase response to tissue injury, infection or other inflammatory stimuli. It is induced by IL1/interleukin-1 and IL6/interleukin-6 -
Isoforms & Post-Translational Modification
P02741 has 2 isomers: P02741-1: 25039 Da (predicted); P02741-2: 10415 Da (predicted).
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Subunit
Homopentamer. Pentraxin (or pentaxin) have a discoid arrangement of 5 non-covalently bound subunits. Interacts with FCN1; may regulate monocyte activation by FCN1
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SwissProt ID
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Synonyms
CRP; PTX1; C-reactive protein
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Research Field
Immunology
Documentation