C9orf167 Antibody (YA7578)
(Synonyms: C9orf167, TOR4A, Torsin-4A, Torsin family 4 member A)C9orf167 Antibody (YA7578) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to C9orf167.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:1000-1:5000 |
Product Details
C9orf167 Antibody (YA7578) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to C9orf167.
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Host Rabbit
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Clonality Monoclonal,Recombinant
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 47 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 47 kDa
The exact sequence is proprietary to MCE.
Endogenous
Protein A affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
C9orf167 (TOR4A) is a member of the Torsin family A, belonging to the AAA+ ATPase superfamily. It is located in the endoplasmic reticulum lumen and nuclear membrane, and participates in protein folding and platelet degranulation. This protein is widely expressed in various tissues. TOR4A, as an oncogene, promotes glioma cell proliferation and survival through the AKT signaling pathway, while DNER can exert a tumor-suppressive effect by inhibiting TOR4A. Furthermore, C9orf167 is a downstream target gene of KLF9 and may be involved in the pathogenesis of endometrial cancer.
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Subcellular Localization
Membrane
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Isoforms & Post-Translational Modification
C9orf167: 423 amino acids, molecular weight 46914 Da.
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SwissProt ID
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Synonyms
C9orf167, TOR4A, Torsin-4A, Torsin family 4 member A
Documentation