Calponin-1 Antibody (YA5530)
(Synonyms: Basic calponin; Calponin 1; Calponin 1 basic smooth muscle; Calponin H1; Calponin H1 smooth muscle; Calponin-1; Calponin1; Calponins basic; CNN 1; Cnn1; CNN1_HUMAN; Epididymis secretory protein Li 14; HEL S 14; Sm Calp; SMCC; smooth muscle)Calponin-1 Antibody (YA5530) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Calponin-1.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
IHC-P, WB, ICC/IF, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|---|
| Dilution Ratio | 1:200-1000 | 1:500-2000 | 1:100-500 | 1:1000-5000 |
Product Details
Calponin-1 Antibody (YA5530) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Calponin-1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 34 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 33 kDa
Synthesized peptide derived from human Calponin-1 AA range: 100-200
Protein G
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Calponin-1 is a Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity
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Expression
Tissue_specificity:Smooth muscle, and tissues containing a large amount of smooth muscle. -
Isoforms & Post-Translational Modification
P51911 has 2 isomers: P51911-1: 33170 Da (predicted); P51911-2: 31055 Da (predicted).
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Subunit
Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1
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SwissProt ID
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Synonyms
Basic calponin; Calponin 1; Calponin 1 basic smooth muscle; Calponin H1; Calponin H1 smooth muscle; Calponin-1; Calponin1; Calponins basic; CNN 1; Cnn1; CNN1_HUMAN; Epididymis secretory protein Li 14; HEL S 14; Sm Calp; SMCC; smooth muscle
Documentation