2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. CCM2 Antibody (YA8152)(PBS only)

CCM2 Antibody (YA8152)(PBS only)

Cat. No.: HY-P88468A
User Guide for Antibodies Technical Support

CCM2 Antibody (YA8152) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CCM2.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

CCM2 Antibody (YA8152) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CCM2.
Host

Mouse
Molecular Weight

Predicted band size: 48.7 kDa
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Immunogen

Full length human recombinant protein of human CCM2 produced in HEK293T cell.
Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:150-500
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:100-250
Purity Affinity purified Conjugation Non-conjugated
Isotype IgG1  
Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions (By similarity). May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock (By similarity)
Subcellular Localization：Cytoplasm
Isoforms & Post-Translational Modification：Q9BSQ5 has four isomers: Q9BSQ5-1: 48837 Da (predicted); Q9BSQ5-2: 51413 Da (predicted); Q9BSQ5-3: 39460 Da (predicted); Q9BSQ5-4: 42073 Da (predicted).
Subunit：Part of a complex with MAP2K3, MAP3K3 and RAC1
Synonyms
C7orf22; OSM; PP10187
Documentation
User Guide for Antibodies (1077 KB)

CCM2 Antibody (YA8152)(PBS only) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CCM2 Antibody (YA8152)(PBS only)
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