CCM2 Antibody (YA8152)(PBS only)
(Synonyms: C7orf22; OSM; PP10187)CCM2 Antibody (YA8152) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CCM2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 |
Product Details
CCM2 Antibody (YA8152) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CCM2.
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Host Mouse
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 48.7 kDa
Full length human recombinant protein of human CCM2 produced in HEK293T cell.
Affinity purified
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CCM2 component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity. May act through the stabilization of endothelial cell junctions. May function as a scaffold protein for MAP2K3-MAP3K3 signaling. Seems to play a major role in the modulation of MAP3K3-dependent p38 activation induced by hyperosmotic shock
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Subcellular Localization
Cytoplasm
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Isoforms & Post-Translational Modification
Q9BSQ5 has four isomers: Q9BSQ5-1: 48837 Da (predicted); Q9BSQ5-2: 51413 Da (predicted); Q9BSQ5-3: 39460 Da (predicted); Q9BSQ5-4: 42073 Da (predicted).
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Subunit
Part of a complex with MAP2K3, MAP3K3 and RAC1
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SwissProt ID
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Synonyms
C7orf22; OSM; PP10187
Documentation
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