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CCR3/CD193 Antibody (YA7084)(PBS only)

(Synonyms: CD193, CMKBR3, CCR3, C-C chemokine receptor type 3, C C CKR3, C-C CKR-3, CC-CKR-3, CCR-3, CKR 3, CKR3, Eosinophil eotaxin receptor)

CCR3/CD193 Antibody (YA7084) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CCR3/CD193.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P, ICC/IF

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • CCR3/CD193 Antibody (YA7084)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
Dilution Ratio 1:500-2000 1:100-200 1:100-200

Product Details

Description

CCR3/CD193 Antibody (YA7084) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CCR3/CD193.

  • Host Rabbit
  • Clonality Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 60kDa;
Immunogen

Purified recombinant fragment of human CD193 expressed in E. Coli.

Sensitivity

Endogenous

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    CCR3/CD193 receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15. Subsequently transduces a signal by increasing the intracellular calcium ions level. In addition acts as a possible functional receptor for NARS1 |(Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection[1][2][3][4].

  • Subcellular Localization

    Cell membrane

  • Expression


    Tissue_Specificity: In eosinophils as well as trace amounts in neutrophils and monocytes

  • Isoforms & Post-Translational Modification

    P51677 has two isomers: P51677-1: 41044 Da (predicted); P51677-2: 43453 Da (predicted).

  • Subunit

    (Microbial infection) Interacts with HIV-1 protein Tat

  • SwissProt ID

    P51677

  • Synonyms

    CD193, CMKBR3, CCR3, C-C chemokine receptor type 3, C C CKR3, C-C CKR-3, CC-CKR-3, CCR-3, CKR 3, CKR3, Eosinophil eotaxin receptor

CCR3/CD193 Antibody (YA7084)(PBS only) Related Classifications

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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • CCR3/CD193 Antibody (YA7084)(PBS only) Product Image