CCR3/CD193 Antibody (YA7084)(PBS only)

Cat. No.: HY-P87396A: Ficha de datos User Guide for Antibodies
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CCR3/CD193 Antibody (YA7084) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CCR3/CD193.

Para uso exclusivo en investigación. No vendemos a pacientes.

Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn
Referencias

Descripciòn

CCR3/CD193 Antibody (YA7084) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CCR3/CD193.

Host

Rabbit

Clonality

Monoclonal

Peso molecular

Predicted band size: 60kDa;

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P51677

Immunogen

Purified recombinant fragment of human CD193 expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-200
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-200

Sensitivity	Endogenous	Pureza	affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Solution

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15 (PubMed:7622448, PubMed:8642344, PubMed:8676064). Subsequently transduces a signal by increasing the intracellular calcium ions level (PubMed:8676064). In addition acts as a possible functional receptor for NARS1 (PubMed:30171954)|(Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection

Subcellular Localization：Cell membrane

Expression：
Tissue_Specificity: In eosinophils as well as trace amounts in neutrophils and monocytes

Isoforms & Post-Translational Modification：P51677 has two isomers: P51677-1: 41044 Da (predicted); P51677-2: 43453 Da (predicted).

Subunit：(Microbial infection) Interacts with HIV-1 protein Tat

Synonyms

CD193, CMKBR3, CCR3, C-C chemokine receptor type 3, C C CKR3, C-C CKR-3, CC-CKR-3, CCR-3, CKR 3, CKR3, Eosinophil eotaxin receptor

Documentación

User Guide for Antibodies (1077 KB)

Referencias

[1]. /biology-dictionary/ht-1080-cell.html [Content Brief]