CD15 Antibody (YA1327)
(Synonyms: ELFT,FCT3A,4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase,ELAM-1 ligand fucosyltransferase,Fucosyltransferase 4,Fuc-TIV; FucT-IV,Galactoside 3-L-fucosyltransferase)CD15 Antibody (YA1327) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD15.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS only.
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:100-1:200 |
Product Details
CD15 Antibody (YA1327) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD15.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 59 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 59 kDa
A synthesized peptide derived from human CD15
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS only.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD15 is a carbohydrate antigen formed by glycosyltransferase catalysis and exists on glycoproteins and glycolipids on the cell surface. CD15 is mainly expressed on neutrophils, eosinophils, and some myeloid cells. Through interaction with selectins such as E-selectin and P-selectin, it mediates leukocyte rolling, adhesion, and migration, playing an important role in acute inflammation and immune defense.
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Subcellular Localization
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein
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Expression
Tissue_specificity:It is expressed at low levels in bone marrow mesenchymal stem cells; it is also expressed in immature promyelocytes in umbilical cord blood and in peripheral blood myeloid and lymphoid cell populations. -
Isoforms & Post-Translational Modification
CD15 has 2 isomers: P22083-1: 59084 Da (predicted); P22083-2: 45629 Da (predicted).
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SwissProt ID
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Synonyms
ELFT,FCT3A,4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase,ELAM-1 ligand fucosyltransferase,Fucosyltransferase 4,Fuc-TIV; FucT-IV,Galactoside 3-L-fucosyltransferase
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Research Field
Immunology
Documentation