CD183 Antibody (YA4663)
(Synonyms: CXCR3; G protein-coupled receptor 9; GPR9; CKR-L2; IP10 receptor; IP10-R; Mig receptor; Mig-R; C-X-C chemokine receptor type 3 antibody; CD 183 antibody; CD182 antibody; CD183 antibody; Chemokine; C X C motif; receptor 3 antibody; Chemokine; C X C; receptor 3 antibody; Chemokine CXC Motif Receptor 3 antibody; CKR L2 antibody; CKR-L2 antibody; CKRL2 antibody; CMKAR3 antibody; CXC-R3 antibody; CXCR-3 antibody; CXCR3 antibody; CXCR3_HUMAN antibody; G Protein Coupled Receptor 9 antibody; G protein-coupled receptor 9 antibody; GPR9 antibody; Interferon-inducible protein 10 receptor antibody; IP-10 receptor antibody; IP10 antibody; IP10 R antibody; IP10 receptor antibody; IP10-R antibody; IP10R antibody; Mig R antibody; Mig receptor antibody; Mig-R antibody; MIGR antibody; )CD183 Antibody (YA4663) is a non-conjugated antibody, targeting to CD183.
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Formulation:
Supplied in Phosphate-buffered solution.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Product Details
CD183 Antibody (YA4663) is a non-conjugated antibody, targeting to CD183.
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Clonality Monoclonal
affinity purified.
Non-conjugated
Unmodified
Product Properties
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Appearance
Liquid
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Formulation
Supplied in Phosphate-buffered solution.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD183 (CXCR3) is a CXC chemokine receptor primarily expressed on activated T cells, Th1 cells, NK cells, and NKT cells. By responding to CXCL9, CXCL10, and CXCL11 signals, CD183 mediates the migration of immune cells to sites of inflammation and tumors; it serves as a key marker for studying Th1 immunity, anti-tumor immunity, immunity against infection, and autoimmune diseases.
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Subcellular Localization
Cell membrane; Multi-pass membrane protein; Cell membrane; Multi-pass membrane protein
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Expression
Tissue_specificity:Isomer 1 and isomer 2 are primarily expressed in the heart, kidneys, liver, and skeletal muscle. Isomer 1 is also expressed in the placenta. Isomer 2 is expressed in endothelial cells. It is also expressed in T cells (protein level) . -
Isoforms & Post-Translational Modification
CD183 (CXCR3) has 3 isomers: P49682-1: 40660 Da (predicted); P49682-2: 45523 Da (predicted); P49682-3: 28715 Da (predicted).
Sulfation on Tyr-27 and Tyr-29 is essential for CXCL10 binding and subsequent signal transduction induction;N-glycosylated -
Subunit
Homomer. Forms heteromers with ACKR4
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SwissProt ID
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Synonyms
CXCR3; G protein-coupled receptor 9; GPR9; CKR-L2; IP10 receptor; IP10-R; Mig receptor; Mig-R; C-X-C chemokine receptor type 3 antibody; CD 183 antibody; CD182 antibody; CD183 antibody; Chemokine; C X C motif; receptor 3 antibody; Chemokine; C X C; receptor 3 antibody; Chemokine CXC Motif Receptor 3 antibody; CKR L2 antibody; CKR-L2 antibody; CKRL2 antibody; CMKAR3 antibody; CXC-R3 antibody; CXCR-3 antibody; CXCR3 antibody; CXCR3_HUMAN antibody; G Protein Coupled Receptor 9 antibody; G protein-coupled receptor 9 antibody; GPR9 antibody; Interferon-inducible protein 10 receptor antibody; IP-10 receptor antibody; IP10 antibody; IP10 R antibody; IP10 receptor antibody; IP10-R antibody; IP10R antibody; Mig R antibody; Mig receptor antibody; Mig-R antibody; MIGR antibody;
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