CD39 Antibody (YA4685)
(Synonyms: ENTPD1; CD39; Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen; CD39; CD39 nanobody; )CD39 Antibody (YA4685) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD39.
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Host:
Mouse
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Application:
ELISA
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Reactivity :
Human
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Formulation:
Supplied in Phosphate-buffered solution.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|
| Dilution Ratio | 1:5000-100000 |
Product Details
Product Properties
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Appearance
Liquid
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Formulation
Supplied in Phosphate-buffered solution.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD39 catalyzes the hydrolysis of both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates and participates in the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow[1][2][3][4].
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Subcellular Localization
Membrane; Multi-pass membrane protein; Membrane, caveola
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Expression
Tissue_specificity:It is primarily expressed on activated lymphocytes (PubMed:7930580) . It is also expressed in endothelial tissues (PubMed:8955160) . It is highly expressed in the placenta, lungs, skeletal muscle, and kidneys (PubMed:8955160) . -
Isoforms & Post-Translational Modification
P49961 has 6 isomers: P49961-1: 57965 Da (predicted); P49961-2: 58706 Da (predicted); P49961-3: 34175 Da (predicted); P49961-4: 42731 Da (predicted); P49961-5: 46180 Da (predicted); P49961-6: 59325 Da (predicted).
N-glycosylated;The N-terminus is blocked;Palmitoylated on Cys-13; which is required for caveola targeting -
Subunit
Homodimer; disulfide-linked
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SwissProt ID
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Synonyms
ENTPD1; CD39; Ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen; CD39; CD39 nanobody;
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