CD97 Antibody (YA1144)(PBS only)

Cat. No.: HY-P81399A: Data Sheet User Guide for Antibodies
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CD97 Antibody (YA1144) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD97.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

CD97 Antibody (YA1144) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD97.

Host

Rabbit

분자량

Predicted band size: 92 kDa;

Observed band size: 75 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P48960

Gene ID

976 [NCBI]

Immunogen

A synthesized peptide derived from human CD97

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-1:200

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration

Subcellular Localization：Cell membrane; Multi-pass membrane protein; Secreted, extracellular space

Expression：
Tissue_specificity:CD97 is widely expressed in most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Smooth muscle cells also express CD97 in large quantities. Furthermore, CD97 is expressed in thyroid cancer, colorectal cancer, gastric cancer, esophageal cancer, and pancreatic cancer. CD97 expression is increased under the inflammatory conditions of the central nervous system in multiple sclerosis and in the synovial tissue of rheumatoid arthritis. Increased CD97 expression in the synovium is accompanied by elevated levels of detectable soluble CD97 in the synovial fluid.

Induction:Rapid up-regulation during lymphocyte activation

Isoforms & Post-Translational Modification：P48960 has 3 isomers: P48960-1: 91869 Da (predicted); P48960-2: 81743 Da (predicted); P48960-3: 86628 Da (predicted).
Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit

Subunit：Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit). Interacts with complement decay-accelerating factor (DAF). The largest isoform (isoform 1) interacts with chondroitin sulfate

Research Field

Neuroscience

Synonyms

ADGRE5; Adhesion G protein-coupled receptor E5; CD97 antigen; Leukocyte antigen CD97; Seven span transmembrane protein; TM7LN1

각종 서류

User Guide for Antibodies (1077 KB)