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Cat. No.: HY-P87659

CDX2 Antibody (YA7344)

CDX2 Antibody (YA7344) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to CDX2.

For research use only. We do not sell to patients.

Formulation:
Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Price

Stock

Quantity

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	IHC-P IHC-P: Immunohistochemistry-Paraffin	WB WB: Western Blot	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence	ELISA ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio	1:500-1:2000	1:2000-1:10000	1:200-1:1000	1:5000-1:20000

Description

CDX2 Antibody (YA7344) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to CDX2.

Host Rabbit
Clonality Monoclonal,Recombinant
Species Reactivity
Human, Mouse, Rat
Observed Molecular Weight

Observed band size: 38 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 34 kDa

Immunogen

The exact sequence is proprietary to MCE.

Sensitivity

Endogenous

Purification

Protein A affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG,Kappa

Appearance

Liquid
Formulation

Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

CDX2 transcription factor which regulates the transcription of multiple genes expressed in the intestinal epithelium. Binds to the promoter of the intestinal sucrase-isomaltase SI and activates SI transcription. Binds to the DNA sequence 5'-ATAAAAACTTAT-3' in the promoter region of VDR and activates VDR transcription. Binds to and activates transcription of LPH. Activates transcription of CLDN2 and intestinal mucin MUC2. Binds to the 5'-AATTTTTTACAACACCT-3' DNA sequence in the promoter region of CA1 and activates CA1 transcription. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. Binds preferentially to methylated DNA^[1].
Subcellular Localization

Nucleus
Expression

Tissue_Specificity: Detected in small intestine, colon and pancreas
Isoforms & Post-Translational Modification

Q99626: 313 amino acids, molecular weight 33520 Da.
Subunit

Can bind DNA as a monomer or homodimer
SwissProt ID

Q99626