DHRS7B Antibody
(Synonyms: CGI-93; SDR32C1; PexRAP)DHRS7B Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to DHRS7B.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IHC-F, ICC/IF, ELISA
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:100-500 | 1:100-500 | 1:100-500 | 1:5000-10000 |
Product Details
DHRS7B Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to DHRS7B.
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Host Rabbit
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size:35 kDa
KLH conjugated synthetic peptide derived from human DHRS7B : aa241-325/325
Affinity purified
Non-conjugated
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DHRS7B is a Reductase required for adipogenesis and activation of PPARG nuclear receptor. Can convert acyl and alkyl dihydroxyacetone-phosphate (DHAP) into glycerolipids and ether lipids, respectively, synthesizing ether-linked phospholipids that act as agonists for PPARG. Also regulates adipogenesis by preventing adipocyte browning: following import into the nucleus, interacts with PRDM16, inhibiting the interaction between PRDM16 and PPARG and preventing differentiation of brown adipocytes
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Subcellular Localization
Peroxisome membrane; Endoplasmic reticulum membrane; Nucleus
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Isoforms & Post-Translational Modification
DHRS7B has an amino acid length of 325, molecular weight is 35119 Da.
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Subunit
Interacts with PRDM16; preventing the interaction between PRDM16 and PPARG
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SwissProt ID
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Synonyms
CGI-93; SDR32C1; PexRAP
Documentation
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