DPEP1/MDP Antibody (YA1231)(PBS only)

Cat. No.: HY-P81486A: Data Sheet User Guide for Antibodies
FAQs
Technical Support

DPEP1/MDP Antibody (YA1231) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DPEP1/MDP.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

DPEP1/MDP Antibody (YA1231) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DPEP1/MDP.

Host

Rabbit

Molecular Weight

Predicted band size: 45.7 kDa;

Observed band size: 40 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P16444

Gene ID

1800 [NCBI]

Immunogen

A synthesized peptide derived from human DPEP1

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-1:200

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4 (PubMed:2303490, PubMed:31442408, PubMed:32325220, PubMed:6334084). Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation (PubMed:32325220). Also possesses beta lactamase activity and can hydrolyze the beta-lactam antibiotic imipenem (PubMed:32325220, PubMed:6334084); Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver

Subcellular Localization：Apical cell membrane; Lipid-anchor, GPI-anchor; Cell projection, microvillus membrane; Lipid-anchor, GPI-anchor

Expression：
Tissue_specificity:Expressed in the lungs and kidneys

Induction:Up-regulated in n colorectal cancers

Subunit：Homodimer; disulfide-linked

Research Field

Cell Biology

Synonyms

DPEP1; MDP; RDP; Dipeptidase 1; Dehydropeptidase-I; Microsomal dipeptidase; Renal dipeptidase

Documentation

User Guide for Antibodies (1077 KB)