EGF Antibody (YA3597)
(Synonyms: URG; HOMG4; EGF)EGF Antibody (YA3597) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EGF.
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Host:
Mouse
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Isotype:
IgG
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Application:
ICC/IF, ELISA
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Reactivity :
Human
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Formulation:
Supplied in ascitic fluid containing 0.03% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:10000 |
Product Details
EGF Antibody (YA3597) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EGF.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 160 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 134 kDa
Purified recombinant fragment of human EGF aa 971-1023.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in ascitic fluid containing 0.03% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Epidermal growth factor (EGF) is the prototypic member of the EGF superfamily of peptide growth factors, which is compose of a single-chain polypeptide containing a total of 53 amino acid residues. EGF is synthesized as a precursor consisting of 1217 amin
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Subcellular Localization
Membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:It is expressed in the kidneys, salivary glands, brain, and prostate. -
Isoforms & Post-Translational Modification
P01133 has 3 isomers: P01133-1: 133994 Da (predicted); P01133-2: 129256 Da (predicted); P01133-3: 129746 Da (predicted).
O-glycosylated with core 1-like and core 2-like glycans. It is uncertain if Ser-954 or Thr-955 is O-glycosylated. The modification here shows glycan heterogeneity: HexHexNAc (major) and Hex2HexNAc2 (minor) -
Subunit
Interacts with EGFR and promotes EGFR dimerization. Interacts with RHBDF2 (By similarity).
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SwissProt ID
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Synonyms
URG; HOMG4; EGF
Documentation