ENT2 Antibody (YA2442)

Cat. No.: HY-P82697: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

ENT2 Antibody (YA2442) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ENT2.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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ENT2 Antibody (YA2442) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

ENT2 Antibody (YA2442) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ENT2.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 50 kDa;

Observed band size: 55-65 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q14542

Gene ID

3177 [NCBI]

Immunogen

Synthetic peptide within human ENT2 aa 1-12/456.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100
FC FC: Flow Cytometry	1:1000

Sensitivity	Endogenous	Purity	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Bidirectional uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis (PubMed:10722669, PubMed:12527552, PubMed:12590919, PubMed:16214850, PubMed:21795683, PubMed:9396714, PubMed:9478986). Functions as a Na(+)-independent, passive transporter (PubMed:9478986). Involved in the transport of nucleosides such as inosine, adenosine, uridine, thymidine, cytidine and guanosine (PubMed:10722669, PubMed:12527552, PubMed:12590919, PubMed:16214850, PubMed:21795683, PubMed:9396714, PubMed:9478986). Also able to transport purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil) (PubMed:16214850, PubMed:21795683). Involved in nucleoside transport at basolateral membrane of kidney cells, allowing liver absorption of nucleoside metabolites (PubMed:12527552). Mediates apical nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis-barrier (PubMed:23639800). Mediates both the influx and efflux of hypoxanthine in skeletal muscle microvascular endothelial cells to control the amount of intracellular hypoxanthine available for xanthine oxidase-mediated ROS production (By similarity); Non functional nucleoside transporter protein for adenosine or thymidine transport. Does not express on cell membrane

Subcellular Localization：Apical cell membrane; Multi-pass membrane protein; Basolateral cell membrane; Multi-pass membrane protein

Expression：
Tissue_specificity:Highly expressed in skeletal muscle (PubMed:9478986) . Expressed in liver, lung, placenta, brain, heart, kidney and ovarian tissues (PubMed:9478986) . Expressed in testis at the blood-brain-barrier (PubMed:23639800)
Positive sample: HeLa cell lysate, K-562 cell lysate, Jurkat cell lysate, SH-SY5Y cell lysate, C2C12 cell lysate, L6 cell lysate, Mouse lung tissue lysate, HepG2, C2C12.

Isoforms & Post-Translational Modification：Q14542 has 4 isomers: Q14542-1: 50113 Da (predicted); Q14542-2: 22276 Da (predicted); Q14542-3: 32507 Da (predicted); Q14542-4: 38758 Da (predicted).
Glycosylated

Database

Entrez Gene: 3177 Human ; 13340 Mouse ; 100911721 Rat 65194

SwissProt: Q14542 Human ; Q61672 Mouse ; Q9JIT8 Mouse ; O54699 Rat

OMIM: 602110 Human

Research Field

Signal Transduction

Synonyms

DER12; ei-type; HNP36; Nucleoside transporter; SLC29A2

Documentation

Select Batch:

Data Sheet (234 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

ENT2 Antibody (YA2442) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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ENT2 Antibody (YA2442)

ENT2 Antibody (YA2442) Featured Recommendations:

Product Detail

Background

Documentation

ENT2 Antibody (YA2442) Related Classifications

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