2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. Ferritin Light Chain Antibody (YA972)

Ferritin Light Chain Antibody (YA972)

Art. -Nr.: HY-P81275A
User Guide for Antibodies Technical Support

Ferritin Light Chain Antibody (YA972) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Ferritin Light Chain.

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20 μL Angebot einholen 3 - 4 Weeks 2 - 3 Weeks 4 - 5 Weeks 3 - 4 weeks
50 μL Angebot einholen 3 - 4 Weeks 2 - 3 Weeks 4 - 5 Weeks 3 - 4 weeks
100 μL Angebot einholen 3 - 4 Weeks 2 - 3 Weeks 4 - 5 Weeks 3 - 4 weeks
250 μL   Angebot einholen  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Beschreibung

Beschreibung

Ferritin Light Chain Antibody (YA972) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Ferritin Light Chain.
Host

Mouse
Clonality

Monoclonal
Molekulargewicht
Predicted band size: 20 kDa;
Observed band size: 20 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

Purified recombinant human TAK1 protein fragments expressed in E.coli.
Application &
Dilution Ratio
Application Dilution Ratio
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
1:10000
Sensitivity Endogenous Reinheit Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG2a  
Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Versand

Shipping with blue ice.
Background
Function：Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity). Delivery to lysosomes by the cargo receptor NCOA4 for autophagic degradation and release or iron (PubMed:24695223)
Subcellular Localization：Cytoplasmic vesicle, autophagosome; Cytoplasm; Autolysosome
Subunit：Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited. Iron enters the spherical protein shell through pores that are formed between subunits. Mutations leading to truncation or the addition of extra residues at the C-terminus interfere with normal pore formation and with iron accumulation. Interacts with NCOA4 (PubMed:24695223)
Database

Entrez Gene: 2512 Human

SwissProt: P02792 Human

OMIM: 600886 Human

Research Field

Neuroscience
Synonyms
Ferritin L chain; Ferritin L subunit; Ferritin light chain; Ferritin light polypeptide; Ferritin light polypeptide like 3; FRIL; FRIL_HUMAN; FTL; L apoferritin; LFTD; MGC71996; NBIA 3; NBIA3.
Dokumentation
User Guide for Antibodies (1077 KB)

Ferritin Light Chain Antibody (YA972) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Ferritin Light Chain Antibody (YA972)
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