Fibulin-2 Antibody (YA4857)
(Synonyms: FBLN2; Fibulin-2; FIBL-2)Fibulin-2 Antibody (YA4857) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Fibulin-2.
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Host:
Mouse
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Application:
WB, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:10000 |
Product Details
Fibulin-2 Antibody (YA4857) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Fibulin-2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 127 kDa;
Purified recombinant fragment of Fibulin-2 (aa180-440) expressed in E. Coli.
Transfected
affinity purified.
Non-conjugated
Unmodified
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Fibulin-2 is an Its binding to fibronectin and some other ligands is calcium dependent. May act as an adapter that mediates the interaction between FBN1 and ELN[1].
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Subcellular Localization
Secreted, extracellular space, extracellular matrix
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Expression
Tissue_specificity:Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary -
Isoforms & Post-Translational Modification
P98095 has 2 isomers: P98095-1: 126573 Da (predicted); P98095-2: 131863 Da (predicted).
O-glycosylated with core 1 or possibly core 8 glycans. It is unsure if the O-glycosylation is on Thr-347 or Ser-348 -
Subunit
Homotrimer; disulfide-linked. Interacts with FBN1 (via N-terminal domain). Forms a ternary complex with ELN and FBN1 (PubMed:17255108)
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SwissProt ID
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Synonyms
FBLN2; Fibulin-2; FIBL-2
Documentation