FOLR1 Antibody (YA1099)(PBS only)

Cat. No.: HY-P81354A: Data Sheet User Guide for Antibodies
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Technical Support

FOLR1 Antibody (YA1099) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Folate Binding Protein.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

FOLR1 Antibody (YA1099) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Folate Binding Protein.

Host

Rabbit

분자량

Predicted band size: 30 kDa;

Observed band size: 40 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P15328

Gene ID

2348 [NCBI]

Immunogen

A synthesized peptide derived from human Folate Binding Protein

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-1:200

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells (PubMed:19074442, PubMed:23851396, PubMed:23934049, PubMed:2527252, PubMed:8033114, PubMed:8567728). Has high affinity for folate and folic acid analogs at neutral pH (PubMed:23851396, PubMed:23934049, PubMed:2527252, PubMed:8033114, PubMed:8567728). Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release (PubMed:8567728). Required for normal embryonic development and normal cell proliferation (By similarity)

Subcellular Localization：Cell membrane; Lipid-anchor, GPI-anchor; Apical cell membrane; Lipid-anchor, GPI-anchor; Basolateral cell membrane; Lipid-anchor, GPI-like-anchor; Secreted; Cytoplasmic vesicle; Cytoplasmic vesicle, clathrin-coated vesicle; Endosome

Expression：
Tissue_specificity:It is primarily expressed in epithelial tissues. Expression increases in malignant tissues. It is expressed in the kidneys, lungs, and cerebellum. It can also be detected in the placental and thymic epithelium.

Research Field

Tags & Cell Markers

Synonyms

FOLR1; FOLR; Folate receptor alpha; FR-alpha; Adult folate-binding protein; FBP; Folate receptor 1; Folate receptor; adult; KB cells FBP; Ovarian tumor-associated antigen MOv18

각종 서류

User Guide for Antibodies (1077 KB)