GLB1/Beta-galactosidase Antibody (YA5563)

Cat. No.: HY-P85871: Data Sheet User Guide for Antibodies
FAQs
Technical Support

GLB1/Beta-galactosidase Antibody (YA5563) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to GLB1/Beta-galactosidase.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

GLB1/Beta-galactosidase Antibody (YA5563) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to GLB1/Beta-galactosidase.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 76 kDa;

Observed band size: 65 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P16278

Gene ID

2720 [NCBI]

Immunogen

AA range: 1-100

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-500
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:1000-5000

Purity	affinity chromatography.	Conjugation	Non-conjugated
Modification	Unmodified

Appearance

Liquid

Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans; Has no beta-galactosidase catalytic activity, but plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. Seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers

Subcellular Localization：Lysosome; Cytoplasm, perinuclear region

Expression：
Tissue_specificity:Protein levels were detected in the placenta (PubMed: 8383699) . It was also detected in fibroblasts and testes (PubMed: 2511208) .

Isoforms & Post-Translational Modification：P16278 has 3 isomers: P16278-1: 76075 Da (predicted); P16278-2: 60536 Da (predicted); P16278-3: 72751 Da (predicted).

Subunit：Homodimer (PubMed:22128166). May form higher multimers (Probable)

Synonyms

GLB1; ELNR1; Beta-galactosidase; Acid beta-galactosidase; Lactase; Elastin receptor 1

Documentation

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/sf9-cell.html [Content Brief]