GLB1/Beta-galactosidase Antibody (YA5563)
(Synonyms: GLB1; ELNR1; Beta-galactosidase; Acid beta-galactosidase; Lactase; Elastin receptor 1)GLB1/Beta-galactosidase Antibody (YA5563) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to GLB1/Beta-galactosidase.
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Host:
Mouse
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Application:
WB, ICC/IF, ELISA
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:100-500 | 1:1000-5000 |
Product Details
GLB1/Beta-galactosidase Antibody (YA5563) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to GLB1/Beta-galactosidase.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 65 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 76 kDa
AA range: 1-100
affinity chromatography.
Non-conjugated
Unmodified
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
GLB1/Beta-galactosidase cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans; Has no beta-galactosidase catalytic activity, but plays functional roles in the formation of extracellular elastic fibers (elastogenesis) and in the development of connective tissue. Seems to be identical to the elastin-binding protein (EBP), a major component of the non-integrin cell surface receptor expressed on fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. In elastin producing cells, associates with tropoelastin intracellularly and functions as a recycling molecular chaperone which facilitates the secretions of tropoelastin and its assembly into elastic fibers
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Subcellular Localization
Lysosome; Cytoplasm, perinuclear region
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Expression
Tissue_specificity:Protein levels were detected in the placenta (PubMed: 8383699) . It was also detected in fibroblasts and testes (PubMed: 2511208) . -
Isoforms & Post-Translational Modification
P16278 has 3 isomers: P16278-1: 76075 Da (predicted); P16278-2: 60536 Da (predicted); P16278-3: 72751 Da (predicted).
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Subunit
Homodimer (PubMed:22128166). May form higher multimers (Probable)
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SwissProt ID
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Synonyms
GLB1; ELNR1; Beta-galactosidase; Acid beta-galactosidase; Lactase; Elastin receptor 1
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