HABP2 Antibody (YA7911)

製品番号: HY-P88227: データシート User Guide for Antibodies
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HABP2 Antibody (YA7911) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to HABP2.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量	価格（税別）	在庫状況
20 μL	$115	見積もりとリードタイムを求めるのご確認
50 μL	$185	見積もりとリードタイムを求めるのご確認
100 μL	$300	見積もりとリードタイムを求めるのご確認

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明
参考文献

製品説明

HABP2 Antibody (YA7911) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to HABP2.

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 60.2 kDa

Species Reactivity

Human

SwissProt ID

Q14520

Immunogen

Human recombinant protein fragment corresponding to amino acids 33-330 of human HABP2 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:2000-2500

Sensitivity	Endogenous	純度	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly (PubMed:11217080). It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form (PubMed:10754382, PubMed:11217080). Activates coagulation factor VII (Probable). May function as a tumor suppressor negatively regulating cell proliferation and cell migration (PubMed:26222560)

Subcellular Localization：Secreted

Expression：
Tissue_Specificity: Ubiquitously expressed

Isoforms & Post-Translational Modification：Q14520 has two isomers: Q14520-1: 62672 Da (predicted); Q14520-2: 59864 Da (predicted).
Proteolytic cleavage at Gly-23 or Met-27 can give rise to the 50 kDa heavy chain (HC) and cleavage at Arg-313 or Lys-319 can give rise to the 27 kDa light chain (LC) (PubMed:8827452)

Subunit：Heterodimer; disulfide-linked

Synonyms

FSAP; HABP; HGFAL; NMTC5; PHBP

ドキュメンテーション

User Guide for Antibodies (1077 KB)

参考文献

[1]. /biology-dictionary/mv4-11-cell.html [Content Brief]