HABP2 Antibody (YA7911)
(Synonyms: FSAP; HABP; HGFAL; NMTC5; PHBP)HABP2 Antibody (YA7911) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to HABP2.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:2000-2500 |
Product Details
HABP2 Antibody (YA7911) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to HABP2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 60.2 kDa
Human recombinant protein fragment corresponding to amino acids 33-330 of human HABP2 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
HABP2 cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII (Probable). May function as a tumor suppressor negatively regulating cell proliferation and cell migration[1][2][3].
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Subcellular Localization
Secreted
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Expression
Tissue_Specificity: Ubiquitously expressed -
Isoforms & Post-Translational Modification
Q14520 has two isomers: Q14520-1: 62672 Da (predicted); Q14520-2: 59864 Da (predicted).
Proteolytic cleavage at Gly-23 or Met-27 can give rise to the 50 kDa heavy chain (HC) and cleavage at Arg-313 or Lys-319 can give rise to the 27 kDa light chain (LC) (PubMed:8827452) -
Subunit
Heterodimer; disulfide-linked
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SwissProt ID
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Synonyms
FSAP; HABP; HGFAL; NMTC5; PHBP
Documentation
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