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HAUS7 Antibody (YA2343)(PBS only)

(Synonyms: UIP1; UCHL5IP)

HAUS7 Antibody (YA2343) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HAUS7.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • HAUS7 Antibody (YA2343)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
Dilution Ratio 1:500-1:1000

Product Details

Description

HAUS7 Antibody (YA2343) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HAUS7.

  • Host Rabbit
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 40 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 40 kDa
Immunogen

Recombinant protein of human UCHL5IP

Purification

Affinity Purified

Conjugation

Non-conjugated

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    HAUS7 contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex

  • Subcellular Localization

    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Cytoplasm, cytoskeleton, spindle

  • Expression


    Tissue_specificity:Detected in spleen, thymus, testis, ovary, small intestine and colon, with highest levels of expression in testis and ovary

  • Isoforms & Post-Translational Modification

    Q99871 has 3 isomers: Q99871-1: 39794 Da (predicted); Q99871-2: 46278 Da (predicted); Q99871-3: 36540 Da (predicted).

  • Subunit

    Component of the HAUS augmin-like complex. The complex interacts with the gamma-tubulin ring complex and this interaction is required for spindle assembly. Interacts with UCHL5 (PubMed:11163772). Interacts with EML3 (phosphorylated at 'Thr-881') (PubMed:30723163)

  • SwissProt ID

    Q99871

  • Gene ID
    55559 [NCBI]
  • Synonyms

    UIP1; UCHL5IP

  • Research Field

    Cell Biology

HAUS7 Antibody (YA2343)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • HAUS7 Antibody (YA2343)(PBS only) Product Image