HOPX Antibody (YA846)

Cat. No.: HY-P80979: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

HOPX Antibody (YA846) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HOPX.

For research use only. We do not sell to patients.

Size	Stock	Quantity
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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HOPX Antibody (YA846) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

HOPX Antibody (YA846) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HOPX.

Host

Rabbit

Clonality

Recombinant, Monoclonal

Molecular Weight

Predicted band size: 8 kDa;

Observed band size: 12 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q8R1H0

Gene ID

74318 [NCBI]

Immunogen

Recombinant protein of mouse HOPX.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IP IP: Immunoprecipitation	1:20

Sensitivity	Endogenous	Purity	Protein A affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (PubMed:12297045, PubMed:12297046). Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding (By similarity)

Subcellular Localization：Nucleus; Cytoplasm

Expression：
Tissue_specificity:Expressed in the embryonic and adult heart and in the adult brain, liver, lung, skeletal muscle, intestine and spleen. Throughout embryonic and postnatal development, it is expressed in the myocardium

Induction:By the transcription factor NKX2-5 that acts as a direct regulator

Subunit：Interacts with serum response factor (SRF) (PubMed:12297045, PubMed:12297046). Component of a large complex containing histone deacetylases such as HDAC2 (PubMed:12975471).

RRID

AB_3102016

Database

Entrez Gene: 74318 Human

SwissProt: Q8R1H0 Human

Synonyms

CAMEO antibody; heart odd homeobox 1 protein antibody; HOD antibody; Homeodomain-only protein antibody; HOP antibody; HOP homeobox antibody; HOP_HUMAN antibody; HOPX antibody; LAGY antibody; Lung cancer-associated Y protein antibody; NECC1 antibody; Not expressed in choriocarcinoma clone 1 antibody; Not expressed in choriocarcinoma protein 1 antibody; OB1 antibody; odd homeobox 1 protein antibody; Odd homeobox protein 1 antibody; OTTHUMP00000158970 antibody; SMAP31 antibody; TOTO antibody;

Documentation

Select Batch:

Data Sheet (232 KB) SDS (254 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

HOPX Antibody (YA846) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HOPX Antibody (YA846)

HOPX Antibody (YA846) Featured Recommendations:

Product Detail

Background

Documentation

HOPX Antibody (YA846) Related Classifications

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