HSD17B4 Antibody (YA7824)
(Synonyms: DBP; MFE-2; MPF-2; PRLTS1; SDR8C1)HSD17B4 Antibody (YA7824) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HSD17B4.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|---|
| Dilution Ratio | 1:1000-4000 | 1:100-250 | 1:150 |
Product Details
HSD17B4 Antibody (YA7824) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HSD17B4.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
Full length human recombinant protein of human HSD17B4 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
HSD17B4 is a Bifunctional enzyme acting on the peroxisomal fatty acid beta-oxidation pathway. Catalyzes two of the four reactions in fatty acid degradation: hydration of 2-enoyl-CoA (trans-2-enoyl-CoA) to produce (3R)-3-hydroxyacyl-CoA, and dehydrogenation of (3R)-3-hydroxyacyl-CoA to produce 3-ketoacyl-CoA (3-oxoacyl-CoA), which is further metabolized by SCPx. Can use straight-chain and branched-chain fatty acids, as well as bile acid intermediates as substrates
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Subcellular Localization
Peroxisome
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Expression
Tissue_Specificity: Present in many tissues with highest concentrations in liver, heart, prostate and testis -
Isoforms & Post-Translational Modification
P51659 has three isomers: P51659-1: 79686 Da (predicted); P51659-2: 83025 Da (predicted); P51659-3: 77870 Da (predicted).
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Subunit
Homodimer
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SwissProt ID
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Synonyms
DBP; MFE-2; MPF-2; PRLTS1; SDR8C1
Documentation