IDH2 Antibody (YA3065)

Cat. No.: HY-P83320: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

IDH2 Antibody (YA3065) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IDH2.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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IDH2 Antibody (YA3065) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

IDH2 Antibody (YA3065) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IDH2.

Host

Rabbit

Clonality

Recombinant, Monoclonal

Molecular Weight

Predicted band size: 51 kDa;

Observed band size: 51 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Rat

SwissProt ID

P48735

Gene ID

3418 [NCBI]

Immunogen

A synthetic peptide of human IDH2

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000

Sensitivity	Endogenous	Purity	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Plays a role in intermediary metabolism and energy production (PubMed:19228619, PubMed:22416140). It may tightly associate or interact with the pyruvate dehydrogenase complex (PubMed:19228619, PubMed:22416140)

Subcellular Localization：Mitochondrion

Isoforms & Post-Translational Modification：P48735 has 2 isomers: P48735-1: 50909 Da (predicted); P48735-2: 45180 Da (predicted).
Acetylation at Lys-413 dramatically reduces catalytic activity. Deacetylated by SIRT3

Subunit：Homodimer

Database

Entrez Gene: 3418 Human ; 269951 Mouse ; 361596 Rat

SwissProt: P48735 Human ; P54071 Mouse ; P56574 Rat

OMIM: 613657 Human

Research Field

Signal Transduction

Synonyms

IDH; IDP; IDHM; IDPM; ICD-M; D2HGA2; mNADP-IDH

Documentation

Select Batch:

Data Sheet (234 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

IDH2 Antibody (YA3065) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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IDH2 Antibody (YA3065)

IDH2 Antibody (YA3065) Featured Recommendations:

Product Detail

Background

Documentation

IDH2 Antibody (YA3065) Related Classifications

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