IL-1F10 Antibody
(Synonyms: FIL1T, IL1HY2, IL38, FKSG75, UNQ6119/PRO20041, IL1F10, Interleukin-1 family member 10, IL-1F10, Family of interleukin 1-theta, Interleukin-1 HY2, Interleukin-1 theta, Interleukin-38, FIL1 theta, IL-1HY2, IL-1 theta, IL-38)IL-1F10 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to IL-1F10.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IHC-P
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 |
Product Details
IL-1F10 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to IL-1F10.
-
Host Rabbit
-
Clonality Polyclonal
-
Species ReactivityHuman, Mouse, Rat
-
Observed Molecular WeightObserved band size: 16 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 16 kDa
Synthetic peptide corresponding to the C-term region of human IL-1F10.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
IL-1F10 is a Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2
-
Subcellular Localization
Cytoplasm; Secreted
-
Expression
Tissue_Specificity: Expressed in fetal skin, spleen and tonsil. Expressed mostly in the basal epithelia of skin and in proliferating B-cells of the tonsil. -
Isoforms & Post-Translational Modification
IL-1F10 has 2 isoforms, Q8WWZ1-1: amino acid length is 152, molecular weight is 16943 Da (predicted); Q8WWZ1-2: amino acid length is 152, molecular weight is 16701 Da (predicted).
-
Subunit
Interacts with cargo receptor TMED10; the interaction mediates the translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and thereby secretion
-
SwissProt ID
-
Synonyms
FIL1T, IL1HY2, IL38, FKSG75, UNQ6119/PRO20041, IL1F10, Interleukin-1 family member 10, IL-1F10, Family of interleukin 1-theta, Interleukin-1 HY2, Interleukin-1 theta, Interleukin-38, FIL1 theta, IL-1HY2, IL-1 theta, IL-38
Documentation
Powered by Bioz
