IL1F10 - interleukin 1 family member 10 Gene

Also Known as IL-38; FKSG75; IL1HY2; IL-1HY2; IL1-theta; FIL1-theta

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84639

About IL1F10

Cytogenetic location: 2q14.1 Genomic coordinates (GRCh38): 2:113,067,970-113,075,843 (from NCBI)

This gene has 3 transcripts (splice variants), 208 orthologues and 7 paralogues. Restricted expression toward skin (RPKM 1.0).

Summary

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight Other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

IL1F10 Products (2)

mRNA Protein Name
NM_032556.6 NP_115945.4 interleukin-1 family member 10
NM_173161.3 NP_775184.1 interleukin-1 family member 10

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

IL1F10 Protein Structure

IL1

IL1: Interleukin-1 / 18 (39 - 147)

  • 0
  • 100
  • 152 a.a.
Protein Preferred Names Protein Names

interleukin-1 family member 10

  • FIL1 theta

Recombinant IL1F10 Proteins

Cat. No. Product Name Accession Purity
HY-P72570 IL-1F10/IL-38 Protein, Human AAI03967.1 (M1-W152) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P76427 IL-1F10/IL-38 Protein, Human (P.pastoris, His) Q8WWZ1 (M1-W152) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P700129AF Animal-Free IL-1F10/IL-38 Protein, Human (His) AAI03967.1 (M1-W152) ≥ 95%, as determined by reducing SDS-PAGE.

IL1F10 Antibodies

Cat. No. Product Name Application Reactivity
HY-P811215 IL-1F10 Antibody WB, IHC-P Human, Mouse, Rat

Related Diseases

Diseases Alias
Psoriasis 11

  • PSORS11

  • Psoriasis Susceptibility 11

  • Psoriasis

  • Psoriasis Vulgaris

  • Psoriasis 11, Susceptibility To

  • Pv
Impetigo Herpetiformis
Psoriasis 14, Pustular

  • Generalized Pustular Psoriasis

  • Gpp

  • Ditra

  • Acrodermatitis Continua Of Hallopeau

  • Palmoplantar Pustulosis

  • PSORS14

  • Interleukin 36 Receptor Antagonist Deficiency

  • Psorp

  • Pustular Psoriasis 14

  • Deficiency Of Il-36r Antagonist

  • Acute Generalised Pustular Psoriasis

  • Deficiency Of The Interleukin-36 Receptor Antagonist

  • Generalized Pustular Psoriasis Of Von Zumbusch

  • Von Zumbusch Psoriasis

  • Deficiency Of Il-36ra

  • Psoriasis, Pustular, Generalized

  • Psoriasis, Pustular, Type 14

  • Pustulosis Of Palms And Soles

  • Acute Generalized Pustular Psoriasis

  • Palmoplantar Pustular Psoriasis

  • Pustulosis Palmaris Et Plantaris

  • Ppp - [Palmoplantar Pustulosis]

  • Pustular Psoriasis Of The Palms And Soles

  • Pustular Bacterid
Periostitis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS19781 Il1f10 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06719 IL1F10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26278 Il1f10 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus IL1F10 MGD MGI:2652548
Bos taurus IL1F10 VGNC VGNC:52788
Canis familiaris IL1F10 VGNC VGNC:49108
Macaca mulatta IL1F10 VGNC VGNC:106172
Rattus norvegicus IL1F10 RGD RGD:1305635
Others IL1F10 NCBI