IL-2 Receptor alpha Antibody (YA2361)
(Synonyms: IL2RA; Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD25)IL-2 Receptor alpha Antibody (YA2361) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-2 Receptor alpha.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P, ICC/IF
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Reactivity :
Human
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Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:50-1:100 | 1:50-1:200 |
Product Details
IL-2 Receptor alpha Antibody (YA2361) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-2 Receptor alpha.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 55-65 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 30 kDa
A synthesized peptide derived from human CD25 aa1-272.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
IL-2 Receptor alpha is an interleukin-2 receptor. IL-2 Receptor alpha participates in the regulation of immune tolerance by controlling the activity of regulatory T cells (TREGs). TREGs inhibit the activation and proliferation of autoreactive T cells.
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Subcellular Localization
Membrane; Single-pass type I membrane protein
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Subunit
Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit
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SwissProt ID
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Synonyms
IL2RA; Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD25
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Research Field
Immunology
Documentation