IL-31 Antibody (YA7043)
(Synonyms: IL 31 antibody; IL-31 antibody; IL31 antibody; IL31_HUMAN antibody; Interleukin 31 antibody; Interleukin-31 antibody)IL-31 Antibody (YA7043) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to IL-31.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
WB, ELISA
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Reactivity :
Human
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Formulation:
Supplied in 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:2000 | 1:5000-1:10000 |
Product Details
IL-31 Antibody (YA7043) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to IL-31.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 18 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 18 kDa
Recombinant protein within Human Interleukin 31 aa 1-164 / 164.
Endogenous
Protein A affinity purified.
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
IL-31 activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. May function in skin immunity. Enhances myeloid progenitor cell survival in vitro. Induces RETNLA and serum amyloid A protein expression in macrophages[1].
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Subcellular Localization
Secreted
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Expression
Tissue_Specificity: Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea
Induction: Up-regulated in skin homing T-cells of patients with atopic dermatitis (AD) and in activated circulating T-cells. Up-regulated in lesional biopsies of patients with allergic contact dermatitis (ACD) -
SwissProt ID
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Synonyms
IL 31 antibody; IL-31 antibody; IL31 antibody; IL31_HUMAN antibody; Interleukin 31 antibody; Interleukin-31 antibody
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