ISYNA1 Antibody (YA6618)

Cat. No.: HY-P86925: Data Sheet User Guide for Antibodies
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ISYNA1 Antibody (YA6618) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ISYNA1.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

ISYNA1 Antibody (YA6618) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ISYNA1.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 61 kDa;

Observed band size: 55-61 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9NPH2

Gene ID

51477 [NCBI]

Immunogen

Recombinant protein within human ISYNA1 aa 1-558.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner (PubMed:15024000, PubMed:23902760). Rate-limiting enzyme in the synthesis of all inositol-containing compounds (PubMed:15024000)

Subcellular Localization：Cytoplasm

Expression：
Tissue_Specificity: Highly expressed in testis, ovary, heart, placenta and pancreas. Weakly expressed in blood leukocyte, thymus, skeletal muscle and colon
Induction: By glucose and lovastain. Up-regulation is prevented by mevalonic acid, farnesol, and geranylgeraniol. Up-regulated by E2F1

Isoforms & Post-Translational Modification：Q9NPH2 has three isomers: Q9NPH2-1: 61068 Da (predicted); Q9NPH2-2: 47146 Da (predicted); Q9NPH2-3: 55136 Da (predicted).
Phosphorylation at Ser-279 and Ser-357 may be associated with a decrease in activity

Synonyms

Inositol-3-phosphate synthase 1 EC:5.5.1.4 IPS 1 Myo-inositol 1-phosphate synthase MI-1-P synthase M; IP : synthase hIPS Myo-inositol 1-phosphate synthase A1 hINO1 ISYNA1 Inositol-3-phosphate synthase 1 EC:5.5.1.4 IPS 1 Myo-inositol 1-phosphate synthase MI-1-P synthase M; IP : synthase hIPS Myo-inositol 1-phosphate synthase A1 hINO1 ISYNA1 INO1

Documentation

User Guide for Antibodies (1077 KB)