ISYNA1 Antibody (YA6618)
(Synonyms: Inositol-3-phosphate synthase 1 EC:5.5.1.4 IPS 1 Myo-inositol 1-phosphate synthase MI-1-P synthase M; IP : synthase hIPS Myo-inositol 1-phosphate synthase A1 hINO1 ISYNA1 Inositol-3-phosphate synthase 1 EC:5.5.1.4 IPS 1 Myo-inositol 1-phosphate synthase MI-1-P synthase M; IP : synthase hIPS Myo-inositol 1-phosphate synthase A1 hINO1 ISYNA1 INO1 )ISYNA1 Antibody (YA6618) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ISYNA1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000 | 1:10000 |
Product Details
ISYNA1 Antibody (YA6618) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ISYNA1.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 55-61 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 61 kDa
Recombinant protein within human ISYNA1 aa 1-558.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
ISYNA1 is key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner. Rate-limiting enzyme in the synthesis of all inositol-containing compounds[1][2].
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Subcellular Localization
Cytoplasm
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Expression
Tissue_Specificity: Highly expressed in testis, ovary, heart, placenta and pancreas. Weakly expressed in blood leukocyte, thymus, skeletal muscle and colon
Induction: By glucose and lovastain. Up-regulation is prevented by mevalonic acid, farnesol, and geranylgeraniol. Up-regulated by E2F1 -
Isoforms & Post-Translational Modification
Q9NPH2 has three isomers: Q9NPH2-1: 61068 Da (predicted); Q9NPH2-2: 47146 Da (predicted); Q9NPH2-3: 55136 Da (predicted).
Phosphorylation at Ser-279 and Ser-357 may be associated with a decrease in activity -
SwissProt ID
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Synonyms
Inositol-3-phosphate synthase 1 EC:5.5.1.4 IPS 1 Myo-inositol 1-phosphate synthase MI-1-P synthase M; IP : synthase hIPS Myo-inositol 1-phosphate synthase A1 hINO1 ISYNA1 Inositol-3-phosphate synthase 1 EC:5.5.1.4 IPS 1 Myo-inositol 1-phosphate synthase MI-1-P synthase M; IP : synthase hIPS Myo-inositol 1-phosphate synthase A1 hINO1 ISYNA1 INO1
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