Cytokeratin 6 Antibody (YA1319)
(Synonyms: Cytokeratin-6C, KRT6C, CK-6C, CK-6E)Cytokeratin 6 Antibody (YA1319) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytokeratin 6.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, Glycerol and BSA
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:500-1:2000 |
Product Details
Cytokeratin 6 Antibody (YA1319) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cytokeratin 6.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size:56 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 60 kDa
Entrez Gene: 286887 Human ; 3853 Human ; 3854 Human ; 16687 Mouse ; 16688 Mouse ;
SwissProt: P02538 Human ; P04259 Human ; P48668 Human ; P50446 Mouse ; Q9Z331 Mouse ;
OMIM: 615726 Human
Peptide
Endogenous
Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS, Glycerol and BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Cytokeratin 6 is a P02538: Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair.
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Expression
Tissue specificity: Constitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath. -
Isoforms & Post-Translational Modification
Cytokeratin 6: 564 amino acids, molecular weight 60,025 Da.
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Subunit
Heterodimer of a type I and a type II keratin. KRT6 isomers associate with KRT16 and/or KRT17
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SwissProt ID
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Synonyms
Cytokeratin-6C, KRT6C, CK-6C, CK-6E
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Research Field
Tumor biology
Documentation