2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. m6A Antibody (YA3446)

m6A Antibody (YA3446) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to m6A.

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100 μL En stock
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Descripciòn

Descripciòn

m6A Antibody (YA3446) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to m6A.
Host

Rabbit
Clonality

Monoclonal,Recombinant
Species Reactivity
Species independent
SwissProt ID

Gene ID
Immunogen

m6A Small Molecule conjugated to OVA.
Application &
Dilution Ratio
Application Dilution Ratio
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
1:1000-1:2000
Dot Blot
 
1:500-1:2000
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Formulation

Supplied in PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Envío

Shipping with blue ice.
Background
Function：N6-methyladenosine (m6A) refers to the methylation modification of the sixth N atom of adenylate (A) in the base composition of RNA. It is the most abundant internal RNA modification in eukaryotes and one of the most common post-transcriptional modifications on RNAs, ubiquitously present in the RNA of living organisms from Escherichia coli to humans. It is found in most RNAs including mRNA, tRNA, rRNA, microRNA, snoRNA, etc., and is particularly prevalent in eukaryotic messenger RNAs (mRNAs). It is dynamic and reversible, catalyzed by RNA methyltransferases such as METTL3, METTL14, and WTAP (called "writers")， removed by demethylases such as fat mass and obesity-associated protein (FTO) and ALKBH5 (ALKB homolog 5) (called "erasers")， and recognized by m6A-binding proteins such as YTHDF domain-containing proteins and IGF2BPs (called "readers"). It participates in the regulation of gene expression through various mechanisms, including RNA alternative splicing, translocation, stability, translation efficiency, nuclear export, localization, and structural transformation, and is widely involved in processes such as cell proliferation, differentiation, embryonic development, and tumorigenesis. Its dysregulation is associated with the pathogenesis of diseases such as cancer, cardiovascular disease, and liver diseases (e.g., liver cancer, viral hepatitis, non-alcoholic fatty liver disease, hepatic fibrosis, acute liver injury, etc.).
Synonyms
m6A antibody; N6-methyladenosine antibody
Documentación
SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)

m6A Antibody (YA3446) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
m6A Antibody (YA3446)
Cat. No.:
HY-P83709
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SAFETY DATA SHEET (SDS)

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