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  3. Monoclonal Antibodies Recombinant Antibodies
  4. MAGE-3 Antibody (YA1109)(PBS only)

MAGE-3 Antibody (YA1109)(PBS only)

製品番号: HY-P81364A
User Guide for Antibodies Technical Support

MAGE-3 Antibody (YA1109) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MAGE-3.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量 在庫状況
50 μL   お問い合わせ  
100 μL   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay
  • Product Detail

  • Background

  • 説明

製品説明

MAGE-3 Antibody (YA1109) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MAGE-3.

Host

Rabbit

分子量
Predicted band size: 35 kDa;
Observed band size: 45 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

Recombinant protein of human MAGEA3

Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:100-1:200
純度 Affinity Purified Conjugation Non-conjugated
Isotype IgG  
Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background
Function:Activator of ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases that acts as a repressor of autophagy (PubMed:20864041, PubMed:31267705). May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex (PubMed:17942928, PubMed:20864041). May play a role in embryonal development and tumor transformation or aspects of tumor progression (PubMed:17942928, PubMed:20864041). In vitro promotes cell viability in melanoma cell lines (PubMed:17942928). Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes (PubMed:8113684)
Expression:
Tissue_specificity:This gene is expressed in various types of tumors, such as melanoma, head and neck squamous cell carcinoma, lung cancer, and breast cancer, but not in normal tissues except for the testes and placenta. It has never been expressed in kidney tumors, leukemia, and lymphoma.
Subunit:Interacts with TRIM28
Research Field

Tags & Cell Markers

Synonyms
HIP8; HYPD; CT1.3; MAGE3; MAGEA6
ドキュメンテーション

MAGE-3 Antibody (YA1109)(PBS only) 関連分類

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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備考

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Inquiry Information

製品名:
MAGE-3 Antibody (YA1109)(PBS only)
製品番号:
HY-P81364A
数量:
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