MAP-1S Antibody (YA8935)
(Synonyms: BPY2IP1, C19orf5, MAP8, VCY2IP1, MAP1S, Microtubule-associated protein 1S, MAP-1S, BPY2-interacting protein 1, Microtubule-associated protein 8, Variable charge Y chromosome 2-interacting protein 1, VCY2-interacting protein 1, VCY2IP-1)Based on 1 Customer Validation
MAP-1S Antibody (YA8935) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to MAP-1S.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, IP, ELISA
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Reactivity :
human
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Formulation:
Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IP
IP: Immunoprecipitation
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:500-1000 | 1-2μg per 100-500μg Total protein | 1:50-3000 |
Product Details
MAP-1S Antibody (YA8935) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to MAP-1S.
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Host Mouse
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Species Reactivityhuman
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Calculated Molecular Weight Predicted band size: 112 kDa
OMIM: 607573
A synthesized peptide derived from human MAP-1S.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at 2-8°C for 1 year, do not freeze.
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Shipping
Shipping with blue ice.
Background
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Function
MAP-1S is a Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity)
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Subcellular Localization
Nucleus; Cytoplasm, cytosol; Cytoplasm, cytoskeleton; Cytoplasm, cytoskeleton, spindle
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Expression
Tissue_Specificity: Expressed in neurons (at protein level). Expressed in spermatocytes, spermatids and spermatozoa. Expressed in the cerebral cortex. Highly expressed in testis. Moderately expressed in the brain, colon, heart, kidney, liver, lung, placenta, small intestine, spleen and stomach. Weakly expressed in muscle. -
Isoforms & Post-Translational Modification
MAP-1S has 2 isoforms, Q66K74-1: amino acid length is 1059, molecular weight is 112211 Da (predicted); Q66K74-2: amino acid length is 1033, molecular weight is 109788 Da (predicted).
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Subunit
Heterodimer of a heavy and a light chain.
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SwissProt ID
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Synonyms
BPY2IP1, C19orf5, MAP8, VCY2IP1, MAP1S, Microtubule-associated protein 1S, MAP-1S, BPY2-interacting protein 1, Microtubule-associated protein 8, Variable charge Y chromosome 2-interacting protein 1, VCY2-interacting protein 1, VCY2IP-1
Documentation