MASP1 HC Antibody
(Synonyms: DNA primase small subunit; DNA primase 49 kDa subunit; p49)MASP1 HC Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to MASP1 HC.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:50-200 |
Product Details
MASP1 HC Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to MASP1 HC.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 49 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 79 kDa
Synthetic peptide corresponding to the center region of human MASP1 HC.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MASP1 HC is a Precursor of a serum protease that activates the complement pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system
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Subcellular Localization
Secreted
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Expression
Tissue_Specificity: Protein of the plasma which is primarily expressed by liver. -
Isoforms & Post-Translational Modification
MASP1 HC has 4 isoforms, P48740-1: amino acid length is 699, molecular weight is 79247 Da (predicted); P48740-2: amino acid length is 728, molecular weight is 81860 Da (predicted); P48740-3: amino acid length is 380, molecular weight is 43640 Da (predicted); P48740-4: amino acid length is 615, molecular weight is 68918 Da (predicted).
Autoproteolytic processing of the proenzyme produces the active enzyme composed on the heavy and the light chain held together by a disulfide bond. -
Subunit
Homodimer.
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SwissProt ID
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Synonyms
DNA primase small subunit; DNA primase 49 kDa subunit; p49
Documentation
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