MAST2 Antibody
(Synonyms: PRA1 family protein 2)MAST2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to MAST2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:50-200 |
Product Details
MAST2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to MAST2.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse
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Observed Molecular WeightObserved band size: 205 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 196 kDa
Synthetic peptide corresponding to the center region of human MAST2.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MAST2 is an Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity)
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Subcellular Localization
Cytoplasm, cytoskeleton; Cell membrane
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Expression
Tissue_Specificity: Abundant in the testis. -
Isoforms & Post-Translational Modification
MAST2 has 2 isoforms, Q6P0Q8-1: amino acid length is 1798, molecular weight is 196436 Da (predicted); Q6P0Q8-2: amino acid length is 1608, molecular weight is 176132 Da (predicted).
Phosphorylated and ubiquitinated. N-terminal ubiquitination leads to degradation of MAST2 by proteasome-mediated proteolysis. -
Subunit
Interacts with CDHR2
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SwissProt ID
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Synonyms
PRA1 family protein 2
Documentation