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MSH3 Antibody (YA6657)

(Synonyms: Divergent upstream protein antibody; DNA mismatch repair protein antibody; DNA mismatch repair protein Msh 3 antibody; DNA mismatch repair protein MSH3 antibody; DUC 1 antibody; DUC1 antibody; DUG antibody; DUP antibody; hMSH3 antibody; MGC163306 antibody; Divergent upstream protein antibody; DNA mismatch repair protein antibody; DNA mismatch repair protein Msh 3 antibody; DNA mismatch repair protein MSH3 antibody; DUC 1 antibody; DUC1 antibody; DUG antibody; DUP antibody; hMSH3 antibody; MGC163306 antibody; MGC163308 antibody; Mismatch repair protein 1 antibody; MRP 1 antibody; MRP1 antibody; MSH 3 antibody; MSH3 antibody; MSH3_HUMAN antibody; MutS homolog 3 (E. coli) antibody; MutS homolog 3 antibody; )
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MSH3 Antibody (YA6657) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MSH3.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, ICC/IF, IHC-P

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Conjugation:
    Non-conjugated
  • MSH3 Antibody (YA6657) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Related Products:
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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:1000-1:2000 1:100 1:200

Product Details

Description

MSH3 Antibody (YA6657) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MSH3.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 127 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 127 kDa
Immunogen

Recombinant protein within human MSH3 aa 201-600.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    MSH3 component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis

  • Subunit

    Component of the DNA mismatch repair (MMR) complex composed at least of MSH2, MSH3, MSH6, PMS1 and MLH1 (PubMed:26300262)

  • SwissProt ID

    P20585

  • Gene ID
    4437 [NCBI]
  • Synonyms

    Divergent upstream protein antibody; DNA mismatch repair protein antibody; DNA mismatch repair protein Msh 3 antibody; DNA mismatch repair protein MSH3 antibody; DUC 1 antibody; DUC1 antibody; DUG antibody; DUP antibody; hMSH3 antibody; MGC163306 antibody; Divergent upstream protein antibody; DNA mismatch repair protein antibody; DNA mismatch repair protein Msh 3 antibody; DNA mismatch repair protein MSH3 antibody; DUC 1 antibody; DUC1 antibody; DUG antibody; DUP antibody; hMSH3 antibody; MGC163306 antibody; MGC163308 antibody; Mismatch repair protein 1 antibody; MRP 1 antibody; MRP1 antibody; MSH 3 antibody; MSH3 antibody; MSH3_HUMAN antibody; MutS homolog 3 (E. coli) antibody; MutS homolog 3 antibody;

MSH3 Antibody (YA6657) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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