MSH3 Antibody (YA6657)

Cat. No.: HY-P86964: Data Sheet COA
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User Guide for Antibodies
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MSH3 Antibody (YA6657) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MSH3.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

MSH3 Antibody (YA6657) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MSH3.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 127 kDa;

Observed band size: 127 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P20585

Gene ID

4437 [NCBI]

Immunogen

Recombinant protein within human MSH3 aa 201-600.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:2000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis

Subunit：Component of the DNA mismatch repair (MMR) complex composed at least of MSH2, MSH3, MSH6, PMS1 and MLH1 (PubMed:26300262)

Synonyms

Divergent upstream protein antibody; DNA mismatch repair protein antibody; DNA mismatch repair protein Msh 3 antibody; DNA mismatch repair protein MSH3 antibody; DUC 1 antibody; DUC1 antibody; DUG antibody; DUP antibody; hMSH3 antibody; MGC163306 antibody; Divergent upstream protein antibody; DNA mismatch repair protein antibody; DNA mismatch repair protein Msh 3 antibody; DNA mismatch repair protein MSH3 antibody; DUC 1 antibody; DUC1 antibody; DUG antibody; DUP antibody; hMSH3 antibody; MGC163306 antibody; MGC163308 antibody; Mismatch repair protein 1 antibody; MRP 1 antibody; MRP1 antibody; MSH 3 antibody; MSH3 antibody; MSH3_HUMAN antibody; MutS homolog 3 (E. coli) antibody; MutS homolog 3 antibody;

Documentation

Select Batch:

Data Sheet (231 KB) SDS (254 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)