MTHFD1L Antibody (YA8947)
(Synonyms: FTHFSDC1, MTHFD1L, Formyltetrahydrofolate synthetase)
Based on 1 Customer Validation
MTHFD1L Antibody (YA8947) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MTHFD1L.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, ICC/IF, IF-Tissue, IP, ELISA
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Reactivity :
human
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Formulation:
Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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IP
IP: Immunoprecipitation
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|---|---|
| Dilution Ratio | 1:500-1000 | 1:50-500 | 1:50-500 | 1-2μg per 100-500μg Total protein | 1:50-3000 |
Product Details
MTHFD1L Antibody (YA8947) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MTHFD1L.
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Host Mouse
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Species Reactivityhuman
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Observed Molecular WeightObserved band size: 110 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 103 kDa
OMIM: 611427
A synthesized peptide derived from human MTHFD1L.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at 2-8°C for 1 year, do not freeze.
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Shipping
Shipping with blue ice.
Background
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Function
MTHFD1L may provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism complementing thus the enzymatic activities of MTHFD2
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Subcellular Localization
Mitochondrion
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Expression
Tissue_Specificity: Detected in most tissues, highest expression found in placenta, thymus and brain. Low expression is found in liver and skeletal muscle. Up-regulated in colon adenocarcinoma. -
Isoforms & Post-Translational Modification
MTHFD1L has 2 isoforms, Q6UB35-1: amino acid length is 978, molecular weight is 105790 Da (predicted); Q6UB35-2: amino acid length is 275, molecular weight is 29804 Da (predicted).
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Subunit
Homodimer
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SwissProt ID
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Synonyms
FTHFSDC1, MTHFD1L, Formyltetrahydrofolate synthetase
Documentation
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