MTHFR Antibody (YA4979)
(Synonyms: MTHFR; Methylenetetrahydrofolate reductase)MTHFR Antibody (YA4979) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MTHFR.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, IHC-P, ELISA
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Reactivity :
Human, Rat
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Formulation:
Supplied in Ascitic fluid containing 0.03% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:1000 | 1:10000 |
Product Details
MTHFR Antibody (YA4979) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to MTHFR.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Rat
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Calculated Molecular Weight Predicted band size: 75kDa;
Purified recombinant fragment of human MTHFR expressed in E. Coli. The exact sequence is proprietary to MCE.
Endogenous
affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in Ascitic fluid containing 0.03% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MTHFR catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine. Represents a key regulatory connection between the folate and methionine cycles (Probable)[1].
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Isoforms & Post-Translational Modification
P42898 has 2 isomers: P42898-1: 74597 Da (predicted); P42898-2: 78965 Da (predicted).
Phosphorylation of an N-terminal serine-rich phosphorylation region increases sensitivity to S-adenosylmethionine and inhibition -
Subunit
Homodimer
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SwissProt ID
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Synonyms
MTHFR; Methylenetetrahydrofolate reductase
Documentation
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