MUC16 Antibody (YA5698)
MUC16 Antibody (YA5698) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MUC16.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
IHC-P, ICC/IF, ELISA
-
Reactivity :
Human
-
Formulation:
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
|---|---|---|---|
| Dilution Ratio | 1:50-100 | 1:50-100 | 1:500-5000 |
Product Details
MUC16 Antibody (YA5698) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MUC16.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman
-
Calculated Molecular Weight Predicted band size: 1519 kDa;
Synthesized peptide derived from human CA 125 AA range: External domain of the CA-125 molecule
affinity chromatography.
Non-conjugated
Unmodified
IgG1
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
MUC16 is a Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces
-
Subcellular Localization
Cell membrane; Single-pass type I membrane protein; Secreted, extracellular space
-
Expression
Tissue_specificity:It is expressed in corneal and conjunctival epithelial cells (protein level) . Compared with normal ovarian tissue and ovarian adenoma, it is overexpressed in ovarian cancer and low-grade malignant potential (LMP) ovarian tumors.
Induction:Up-regulated in ovarian cancer cells -
Subunit
Binds to MSLN. Binding to MSLN mediates heterotypic cell adhesion. This may contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to MSLN
-
SwissProt ID
Documentation
Powered by Bioz
