MUC16 Antibody (YA5698)

Cat. No.: HY-P86006: Data Sheet User Guide for Antibodies
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MUC16 Antibody (YA5698) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MUC16.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

MUC16 Antibody (YA5698) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MUC16.

Host

Mouse

Clonality

Monoclonal

분자량

Predicted band size: 1519 kDa;

Species Reactivity

Human

SwissProt ID

Q8WXI7

Gene ID

94025 [NCBI]

Immunogen

Synthesized peptide derived from human CA 125 AA range: External domain of the CA-125 molecule

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-100
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:500-5000

Purity	affinity chromatography.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces

Subcellular Localization：Cell membrane; Single-pass type I membrane protein; Secreted, extracellular space

Expression：
Tissue_specificity:It is expressed in corneal and conjunctival epithelial cells (protein level) . Compared with normal ovarian tissue and ovarian adenoma, it is overexpressed in ovarian cancer and low-grade malignant potential (LMP) ovarian tumors.

Induction:Up-regulated in ovarian cancer cells

Subunit：Binds to MSLN. Binding to MSLN mediates heterotypic cell adhesion. This may contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to MSLN

각종 서류

User Guide for Antibodies (1077 KB)