MUM1 Antibody (YA7122)(PBS only)
(Synonyms: EXPAND1, MUM1, PWWP3A, PWWP domain-containing DNA repair factor 3A, Mutated melanoma-associated antigen 1, PWWP domain-containing protein MUM1, Protein expandere, MUM-1)MUM1 Antibody (YA7122) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MUM1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:10000 |
Product Details
MUM1 Antibody (YA7122) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MUM1.
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Host Mouse
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 78.6kDa;
Purified recombinant fragment of human MUM1 expressed in E. Coli.
affinity purified.
Non-conjugated
IgG1
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MUM1 is involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
Q2TAK8 has three isomers: Q2TAK8-1: 78636 Da (predicted); Q2TAK8-2: 70733 Da (predicted); Q2TAK8-3: 80700 Da (predicted).
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Subunit
Interacts with TP53BP1 (via BRCT domain); the interaction is not dependent on its phosphorylation status
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SwissProt ID
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Synonyms
EXPAND1, MUM1, PWWP3A, PWWP domain-containing DNA repair factor 3A, Mutated melanoma-associated antigen 1, PWWP domain-containing protein MUM1, Protein expandere, MUM-1
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