MUM1 Antibody (YA7122)
MUM1 Antibody (YA7122) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MUM1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:200-1:1000 | 1:10000 |
Product Details
MUM1 Antibody (YA7122) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MUM1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 78.6kDa;
SwissProt: SwissProt: Q2TAK8
Purified recombinant fragment of human MUM1 expressed in E. Coli.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MUM1 is involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
Q2TAK8 has three isomers: Q2TAK8-1: 78636 Da (predicted); Q2TAK8-2: 70733 Da (predicted); Q2TAK8-3: 80700 Da (predicted).
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Subunit
Interacts with TP53BP1 (via BRCT domain); the interaction is not dependent on its phosphorylation status
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SwissProt ID
Documentation
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