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MYOT Antibody (YA8373)

(Synonyms: LGMD1; LGMD1A; MFM3; TTID; TTOD)

MYOT Antibody (YA8373) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MYOT.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Conjugation:
    Non-conjugated
  • Experimental Validation Results for MYOT Antibody (YA8373)
  • MYOT Antibody (YA8373) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:800-1500

Product Details

Description

MYOT Antibody (YA8373) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MYOT.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 55.2 kDa
Immunogen

Full length human recombiant protein of human MYOT produced in E.coli.

Sensitivity

Endogenous

Purification

Affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Verification Images

  • Experimental Validation Results for MYOT Antibody (YA8373)
    Immunohistochemical analysis of paraffin-embedded human striated muscle using MYOT antibody. The section was pre-treated using heat mediated antigen retrieval with EDTA (pH 9.0) for 14 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with TBST, and then probed with the primary antibody (HY-P88689, 1/1000) for 30 minutes at room temperature. The detection was performed using Polymer HRP-conjugated Goat Anti-Mouse/Rabbit lgG(H&L) secondary antibody (HY-P83652). DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

Background

  • Function

    MYOT component of a complex of multiple actin cross-linking proteins. Involved in the control of myofibril assembly and stability at the Z lines in muscle cells

  • Subcellular Localization

    Cell membrane, sarcolemma,Cytoplasm, cytoskeleton,Cytoplasm, myofibril, sarcomere, Z line

  • Expression


    Tissue_Specificity: Expressed in skeletal muscle (at protein level). Expressed in skeletal muscle, heart, bone marrow and thyroid gland

  • Isoforms & Post-Translational Modification

    Q9UBF9 has two isomers: Q9UBF9-1: 55395 Da (predicted); Q9UBF9-2: 35147 Da (predicted).

  • Subunit

    Homodimer

  • SwissProt ID

    Q9UBF9

  • Synonyms

    LGMD1; LGMD1A; MFM3; TTID; TTOD

MYOT Antibody (YA8373) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • 1/16

    MedChemExpress Validation
     Immunohistochemical analysis of paraffin-embedded human striated muscle using MYOT antibody. The section was pre-treated using heat mediated antigen retrieval with EDTA (pH 9.0) for 14 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with TBST, and then probed with the primary antibody (HY-P88689, 1/1000) for 30 minutes at room temperature. The detection was performed using Polymer HRP-conjugated Goat Anti-Mouse/Rabbit lgG(H&L) secondary antibody (HY-P83652). DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

  • MYOT Antibody (YA8373) Product Image
    1/16
  • Experimental Validation Results for MYOT Antibody (YA8373)
  • MYOT Antibody (YA8373) Product Image
  • Experimental Validation Results for MYOT Antibody (YA8373)
    1/1
    MedChemExpress Validation
     Immunohistochemical analysis of paraffin-embedded human striated muscle using MYOT antibody. The section was pre-treated using heat mediated antigen retrieval with EDTA (pH 9.0) for 14 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with TBST, and then probed with the primary antibody (HY-P88689, 1/1000) for 30 minutes at room temperature. The detection was performed using Polymer HRP-conjugated Goat Anti-Mouse/Rabbit lgG(H&L) secondary antibody (HY-P83652). DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
  • Experimental Validation Results for MYOT Antibody (YA8373)
  • MYOT Antibody (YA8373) Product Image
    MedChemExpress Validation

    Immunohistochemical analysis of paraffin-embedded human striated muscle using MYOT antibody. The section was pre-treated using heat mediated antigen retrieval with EDTA (pH 9.0) for 14 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with TBST, and then probed with the primary antibody (HY-P88689, 1/1000) for 30 minutes at room temperature. The detection was performed using Polymer HRP-conjugated Goat Anti-Mouse/Rabbit lgG(H&L) secondary antibody (HY-P83652). DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

  • MYOT Antibody (YA8373) Product Image IHC-P